高等学校化学学报

高等学校化学学报

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纳米羟基磷灰石/溶菌酶复合体的原位合成及酶活性研究

王春艳1,2, 朱广山1, 高波3, 王润伟1, 李娟2, 辛明红1, 裘式纶1   

    1. 吉林大学无机合成与制备化学国家重点实验室, 长春 130012;
    2. 吉林大学公共卫生学院, 长春 130021;
    3. 吉林大学生命科学学院, 长春 130023
  • 收稿日期:2005-06-02 修回日期:1900-01-01 出版日期:2006-08-10 发布日期:2006-08-10
  • 通讯作者: 裘式纶

In-situ Synthesis and Activity of Nano-hydroxyapatite/Lysozyme Composite

WANG Chun-Yan1,2, ZHU Guang-Shan1, GAO Bo3, WANG Run-Wei1, LI Juan2, XIN Ming-Hong1, QIU Shi-Lun1   

    1. State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012;
    2. School of Public Health, Jilin University, Changchun 130021;
    3. College of Life Science, Jilin University, Changchun 130023, China
  • Received:2005-06-02 Revised:1900-01-01 Online:2006-08-10 Published:2006-08-10
  • Contact: QIU Shi-Lun

PDF (PC)

被引次数

6

摘要：

利用一种新的溶菌酶的组装方法, 湿法合成原位组装了羟基磷灰石/溶菌酶复合体, 对组装体进行多种表征并与浸渍组装的方法进行了对比.

关键词: 纳米羟基磷灰石, 溶菌酶, 合成, 活性

Abstract: Nano-composite of hydroxyapatite/lysozyme with a size of 100 nm was synthesized in situ by chemical wet method, and characterized by nitrongen gas adsorption method, IR, SEM and UV-Vis spectroscopic techniques. In comparison with that synthesized by the dipping adsorbing method, the composite synthesized by wet method has much more content and activity of lysozyme. These results suggest the composite can be used as a controlling carrier of releasing lysozyme.

Key words: Hydroxyapatite, Lysozyme, Synthesis, Activity

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