多重敏感性双亲共聚物P(DM-co-AA-co-CA)的自组装及性能

高等学校化学学报 ›› 2011, Vol. 32 ›› Issue (8): 1889.

多重敏感性双亲共聚物P(DM-co-AA-co-CA)的自组装及性能

顾辛艳, 易成林, 卢杨斌, 范存华, 江金强, 刘晓亚

江南大学化学与材料工程学院, 无锡 214122

收稿日期:2010-09-21 修回日期:2010-12-30 出版日期:2011-08-10 发布日期:2011-07-19
通讯作者: 刘晓亚;江金强 E-mail:lxy@jiangnan.edu.cn; jiangjq@jiangnan.edu.cn
基金资助:
国家自然科学基金(批准号: 20974041, 50673038)资助.

Self-assembly and Properties of Multi-sensitive Amphiphilic P(DM-co-AA-co-CA) Copolymer

GU Xin-Yan, YI Cheng-Lin, LU Yang-Bin, FAN Cun-Hua, JIANG Jin-Qiang*, LIU Xiao-Ya*

School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China

Received:2010-09-21 Revised:2010-12-30 Online:2011-08-10 Published:2011-07-19
Contact: LIU Xiao-Ya;JIANG Jin-Qiang E-mail:lxy@jiangnan.edu.cn; jiangjq@jiangnan.edu.cn
Supported by:
国家自然科学基金(批准号: 20974041, 50673038)资助.

摘要/Abstract

摘要： 以甲基丙烯酸二甲胺乙酯（DM）、丙烯酸（AA）和香豆素丙烯酸酯化物（CA）为共聚单体，通过普通自由基溶液聚合合成了多重敏感性双亲共聚物P(DM-co-AA-co-CA)，用傅里叶变换红外（FTIR）、核磁共振（1H-NMR）、凝胶渗透色谱（GPC）和差示扫描量热仪（DSC）对聚合物结构进行表征．在选择性溶剂四氢呋喃/水中对所得多重敏感性双亲共聚物P(DM-co-AA-co-CA)进行自组装，结果表明，调节组装环境的pH值可以得到荷正电或负电的两性胶束粒子．用紫外可见光分光光度计、荧光分光光度计、Zeta电位测定仪、DLS和TEM研究了多重敏感性双亲共聚物的溶液自组装及其组装体的性能，结果显示，调节pH值可以有效的控制胶束的粒径大小及其LCST，并在pH为8.54时胶束溶液的紫外吸收和荧光发射强度达到最大值，且该胶束溶液在酸碱性较强时具有良好的乳化性能．

关键词: 双亲共聚物, 自组装, 多重敏感性, 胶束

Abstract: Coumarin-containing acrylic acid monomer(CA) was designed and synthesized，which could be used together with dimethylaminoethyl methacrylate(DM) and acrylic acid(AA) to synthesize the multi-sensitive amphiphilic copolymer P(DM-co-AA-co-CA) via free radical copolymerization. Its structure was characterized by Fourier transform Infrared Spectroscopic (FTIR)、Magnetic Resonance Spectrometer (1H-NMR), Gel Permeation Chromatography (GPC) and Differential Scanning Calorimeter (DSC). The copolymer could self-assemble into steady spherical micelles in the selective solvent THF/water with suitable initial copolymer concentration and water content. The self-assembly process and characteristic of P(DM-co-AA-co-CA) micelles were studied by UV spectrophotometer、fluorescence spectrophotometer、Zeta Potential、Dynamic laser light Scattering(DLS) and Transmission Electron Microscope(TEM). The results show that in the range of pH=2.13-8.54, the UV absorbance and fluorescence emission intensity of micellar solutions increased with increasing of pH, and in the range of 8.54-12.46, both of them decreased with increasing of pH value. Depending on the solution pH, these micelles can exist in two different micellar charge states and also exhibits an isoelectric point at around pH 9.70, around which the diameter of micelle particles became the smallest, and then it increased either with the pH increasing or decreasing. In basic solution, LCST of micelles decreased with increasing of pH value, and such amphiphilic micelles are of efficient emulsification properties in pH 1.16 and 12.62.

Key words: Amphiphilic copolymer, Self-assembly, Multi-sensitive, Micelle

中图分类号:

O648

TrendMD:

顾辛艳, 易成林, 卢杨斌, 范存华, 江金强, 刘晓亚. 多重敏感性双亲共聚物P(DM-co-AA-co-CA)的自组装及性能. 高等学校化学学报, 2011, 32(8): 1889.

GU Xin-Yan, YI Cheng-Lin, LU Yang-Bin, FAN Cun-Hua, JIANG Jin-Qiang*, LIU Xiao-Ya*. Self-assembly and Properties of Multi-sensitive Amphiphilic P(DM-co-AA-co-CA) Copolymer. Chem. J. Chinese Universities, 2011, 32(8): 1889.

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