石墨烯基环糊精传感器的构建及对组氨酸对映体的电位识别

doi:10.7503/cjcu20180562

高等学校化学学报 ›› 2019, Vol. 40 ›› Issue (2): 230.doi: 10.7503/cjcu20180562

石墨烯基环糊精传感器的构建及对组氨酸对映体的电位识别

吴燕, 连惠婷, 孙向英, 刘斌()

华侨大学材料科学与工程学院, 分子设计与绿色转化福建省高校重点实验室, 厦门 361021

收稿日期:2018-08-10 出版日期:2019-02-10 发布日期:2018-12-27
作者简介:
联系人简介: 刘斌, 男, 教授, 主要从事光电化学传感器方面的研究. E-mail: bliu@hqu.edu.cn
基金资助:
国家自然科学基金(批准号: 21575044)、福建省自然科学基金(批准号: 2015J01054, 2016J01062)和福建省石墨烯粉体及复合材料工程技术研究中心建设项目(批准号: 2017H2001)资助

Construction of Cyclodextrin Polymeric Membrane Sensor Based on Graphene and Potential Recognition for Histidine Enantiomer^†

WU Yan, LIAN Huiting, SUN Xiangying, LIU Bin^*()

College of Materials Science and Engineering, Huaqiao University, Key Laboratory of Molecular Designing and Green Conversions(Fujian University), Xiamen 361021, China

Received:2018-08-10 Online:2019-02-10 Published:2018-12-27
Contact: LIU Bin E-mail:bliu@hqu.edu.cn
Supported by:
† Supported by the National Natural Science Foundation of China(No.21575044), the Natural Science Foundation of Fujian Province, China(Nos.2015J01054, 2016J01062) and the Foundation of Graphene Powder & Composite Research Center of Fujian Province, China(No.2017H2001)

摘要/Abstract

摘要：

以具备手性识别作用的环糊精聚合物为手性选择剂, 以石墨烯为手性放大材料, 通过层层修饰的方法构建了石墨烯基环糊精聚合膜电位识别传感器. 由所构建的传感器测得的组氨酸对映体的氧化峰电位存在明显的差异, 电位差值近100 mV, 且不同比例的组氨酸对映体混合溶液的氧化峰电位值与对映体过量值呈现良好的线性关系. 据此, 建立了一种通过电位同时识别组氨酸对映体两组分的新方法.

关键词: 组氨酸对映体, 电位识别, 石墨烯, 环糊精

Abstract:

Cyclodextrin polymer with chiral recognition function were selected as chiral selectors, and graphene materials with excellent performance were used to further amplify the difference in peak potential response, cyclodextrin polymeric membrane sensor based on graphene was constructed by layer modification. There was a significant difference in the peak potential response between two components of histidine enantiomer. The potential difference is nearly 100 mV. A good linear relationship was showed between the oxidation peak potential and enantiomeric excess of the mixed solution. The mixed solution consists of different ratios of two components histidine enantiomer. A new method for simultaneously identifying two components of histidine enantiomer by potential response can be established.

Key words: Histidine enantiomer, Potential recognition, Graphene, Cyclodextrin

中图分类号:

O657

TrendMD:

吴燕, 连惠婷, 孙向英, 刘斌. 石墨烯基环糊精传感器的构建及对组氨酸对映体的电位识别. 高等学校化学学报, 2019, 40(2): 230.

WU Yan,LIAN Huiting,SUN Xiangying,LIU Bin. Construction of Cyclodextrin Polymeric Membrane Sensor Based on Graphene and Potential Recognition for Histidine Enantiomer^†. Chem. J. Chinese Universities, 2019, 40(2): 230.

图/表 14

Scheme 1 Schematic illustration for the preparation of the PCD/rGO/GCE and recognition for His

Fig.1 DPV responses of histidine enantiomer on the GCE(A), PCD/GCE(B) and PCD/rGO/GCE(C)The arrows of (A)—(C) show the potential scan direction.

Fig.2 Potential difference of D/L-His on PCD/rGO/GCE with different concentrations of GO(A) and with different reduction cycles of GO(B)

Fig.3 Potential difference of D/L-His on PCD/rGO/GCE with different polymerized cycles of CD(A) and with different concentrations of CD polymerized solution(B)

Fig.4 Potential difference of the D/L-His on PCD/rGO/GCE with different pH(A) and the oxidation potential of histidine enantiomer with different pH values(B)

Fig.5 CV curves in the electro-polymerization of CD

Fig.6 High-resolution XPS spectra of C1s(A), O1s(B) of PCD

Fig.7 SEM images of GCE(A), rGO(B) and PCD/rGO(C)

Fig.8 Raman spectra of GO(a), rGO(b) and PCD/rGO(c)

Fig.9 Recognition of the D/L-His on GCE(A) and PCD/rGO/GCE(B) with EIS

Scheme 2 Schematic illustration for establishment of potential identification methodThe arrows of (A)—(C) show the potential scan direction.

Fig.10 DPV response of PCD/rGO/GCE sensor for different ratio of L/D-His(total concentration 100 μmol/L)(A) and the curve of peak potential Ep to e.e. value(B)The arrow of (A) shows the potential scan direction.

Table 1 Change of potential(E/V) for the ratios of 5:5, 3:7 and 7:3 between L-His and D-His

L-His to D-His ratio	c/(μmol·L^-1)
L-His to D-His ratio	30	50	70	80	100	200	500	800	1000
5:5	1.143	1.140	1.128	1.125	1.125	1.124	1.125	1.125	1.125
3:7	1.100	1.100	1.090	1.090	1.090	1.090	1.095	1.090	1.092
7:3	1.068	1.165	1.150	1.150	1.150	1.152	1.150	1.150	1.150

Fig.11 Response ratio(ΔE/ΔE0) of the PD of L/D-His on PCD/rGO/GCE in the presence of 1 and 10 times of the concentration of chiral coexistences(A), recognition of the His, tryptophan and tyrosine on PCD/rGO/GCE(B)(A) a. L-Tyr; b. D-Tyr; c. L-Trp; d. D-Trp; e. L-Pen; f. D-Pen; g. L-Pro; h. D-Pro.

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石墨烯基环糊精传感器的构建及对组氨酸对映体的电位识别

Construction of Cyclodextrin Polymeric Membrane Sensor Based on Graphene and Potential Recognition for Histidine Enantiomer^†

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石墨烯基环糊精传感器的构建及对组氨酸对映体的电位识别

Construction of Cyclodextrin Polymeric Membrane Sensor Based on Graphene and Potential Recognition for Histidine Enantiomer†

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Construction of Cyclodextrin Polymeric Membrane Sensor Based on Graphene and Potential Recognition for Histidine Enantiomer^†