高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (4): 751.

• 研究简报 • 上一篇    下一篇

导电原子力显微镜对蛋白质在分子水平上的电学表征

赵健伟1, 王楠2   

  1. 1. 南京大学化学化工学院, 南京 210093;
    2. 重庆大学化学化工学院, 重庆 400044
  • 收稿日期:2004-04-20 出版日期:2005-04-10 发布日期:2005-04-10
  • 通讯作者: 赵健伟(1972年出生),男,教授,主要从事分子电化学和分子电子学研究.E-mail:zhaojw@nju.edu.cn E-mail:zhaojw@nju.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:20435010)资助.

Electricity Characterization of Metalloprotein at Molecular Level by Conducting Atomic Force Microscopy

ZHAO Jian-Wei1, WANG Nan2   

  1. 1. Department of Chemistry, Nanjing University, Nanjing 210093, China;
    2. Department of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China
  • Received:2004-04-20 Online:2005-04-10 Published:2005-04-10

关键词: 导电原子力显微镜, 蛋白质, 介电强度

Abstract: The electric and dielectric properties of metalloprotein, azurin, were studied at real molecular level by using conducting atomic force microscopy(C-AFM). Under a force lower than 2 nN, dielectric breakdown was observed. When reliable electrical contact between electrodes and protein is achieved under a force greater than 5 nN, well-behaved current-voltage characters are revealed, and dependent on the force load.

Key words: Conducting atomic force microscopy, Protein, Dielectric strength

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