高等学校化学学报 ›› 2003, Vol. 24 ›› Issue (1): 91.

• 论文 • 上一篇    下一篇

微量热法研究硒对砷在大肠杆菌生长中的联合作用

李曦1, 刘义2, 吴军2, 屈松生2   

  1. 1. 武汉理工大学材料复合新技术国家重点实验室, 武汉 430070;
    2. 武汉大学化学与分子科学学院, 武汉 430072
  • 收稿日期:2001-10-31 出版日期:2003-01-24 发布日期:2003-01-24
  • 通讯作者: 李 曦(1968年出生),女,博士,副教授,从事生物材料研究.E-mail:chemlixi@mail.whut.edu.cn E-mail:chemlixi@mail.whut.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:29973030,30170010)资助

Microcalorimetric Study of the Associated Action of Selenium to Arsenic on the Growth of Escherichia coli

LI Xi1, LIU Yi2, WU Jun2, QU Song-Sheng2   

  1. 1. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China;
    2. Collage of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, China
  • Received:2001-10-31 Online:2003-01-24 Published:2003-01-24

摘要: 以大肠杆菌为模型生物,结合生物学的细菌培养方法,用微量热法研究了硒代吗啉与亚砷酸钠对大肠杆菌的联合作用,初步探讨了它们之间的作用机理.结果表明,硒代吗啉和亚砷酸钠之间既有拮抗作用,也有协同作用,这依赖于两者的相对浓度.硒与砷的作用机理可能与细菌生长代谢过程中酶的合成有关.

关键词: 微量热法, 硒代吗啉, 亚砷酸钠, 联合作用, 大肠杆菌

Abstract: Escherichia coli was used as an experimental object, the associated action between selenomorpholine and sodium arsenite was studied by microcalorimetry. The experiment results showed that there was antagonistic or cooperative interaction between selenomorpholine and sodium arsenite, and whether antagonistic or cooperative interaction between selenium and arsenic depended on their relative concentrations. The mechanism of the associated action between selenomorpholine and sodium arsenite perhaps is due to the synthesis of the enzyme in the growth of the bacteria.

Key words: Microcalorimetry, Selenomorpholine, Sodium arsenite, Associated action, Escherichia coli

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