高等学校化学学报

高等学校化学学报 ›› 2003, Vol. 24 ›› Issue (1): 76.

• 研究简报 • 上一篇    下一篇

醛和胺原位生成的手性亚胺盐催化的不对称环氧化

郑炎松, 江岸   

  1. 华中科技大学化学系, 武汉 430074
  • 收稿日期:2001-11-09 出版日期:2003-01-24 发布日期:2003-01-24
  • 通讯作者: 郑炎松(1961年出生),男,博士,副教授,从事有机化学及高分子化学研究.E-mail:yszh@public.wh.hb.cn E-mail:yszh@public.wh.hb.cn
  • 基金资助:

    国家自然科学基金(批准号:20072007);华中理工大学科学基金资助

Asymmetric Epoxidation of Olefins Catalyzed by Chiral Iminium Salts Generated in situ from Chiral Amines and Aldehydes

ZHENG Yan-Song, JIANG An   

  1. Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074, China
  • Received:2001-11-09 Online:2003-01-24 Published:2003-01-24

PDF (PC)

被引次数

15

关键词: 不对称环氧化, 手性胺, 醛, 手性亚胺盐, 过硫酸氢钾制剂(Oxone)

Abstract: Asymmetric epoxidation of olefins with oxone was first catalyzed by chiral iminium salts generated in situ from chiral amines and aldehydes. With 2S,5S-2,5-dicyclohexylaminocarbonylpyrolidine and t-butylacetaldehyde, trans-stilbene were epoxdized in 80% conversion, 93% yield and 65% e.e. at 0 ℃.

Key words: Asymmetric epoxidation, Chiral amine, Aldehyde, Iminium salt, Oxone

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