高等学校化学学报

高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (7): 1230.

• 研究论文 • 上一篇    下一篇

Fe(Ⅱ)-EDTA剪切DNA在悬汞电极上的电化学行为研究

李美仙, 李南强   

  1. 北京大学化学与分子工程学院, 北京 100871
  • 收稿日期:1999-11-30 出版日期:2001-07-24 发布日期:2001-07-24
  • 通讯作者: 李南强(1932年出生),男,教授,博士生导师,从事电分析化学研究.
  • 基金资助:

    国家自然科学基金(批准号:209835110)

Studies on Electrochemical Behavior of Fe(Ⅱ)-EDTA Cleaving DNA on HMDE

LI Mei-Xian, LI Nan-Qiang    

  1. College of Chemistry and Molecular Engineering, Peking University, Bejing 100871, China
  • Received:1999-11-30 Online:2001-07-24 Published:2001-07-24

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被引次数

15

关键词: Fe(Ⅱ)-EDTA, 剪切, DNA, 电化学

Abstract: Electrochemical behavior of Fe(Ⅱ)-EDTAcleaving DNAon hanging mercury drop electrode(HMDE) was studied. It was found that the changes in the DNAstructure due to Fe(Ⅱ)-EDTAbreaking DNAresult in the increasing of a reduction peak current of DNAon HMDE, indicating that the electrochemical methods are hopeful to be used as an auxiliary means for probing changes in the DNAstructure. Furthermore, the standard rate constant of the surface reaction k s was determined as 0.59 s-1.

Key words: Fe(Ⅱ) EDTA, Cleaving, DNA, Electrochemistry

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