高等学校化学学报 ›› 1997, Vol. 18 ›› Issue (10): 1729.

• 论文 • 上一篇    下一篇

一种新型甘油三酯吸附剂的制备及其对血清中甘油三酯的吸附性能研究

余艺华1, 孙君坦1, 何炳林1, 顾汉卿2   

  1. 1. 南开大学高分子化学研究所, 天津 300071;
    2. 天津泌尿外科研究所, 天津 300211
  • 收稿日期:1996-07-09 出版日期:1997-10-24 发布日期:1997-10-24
  • 通讯作者: 余艺华, 男, 27岁, 博士研究生.
  • 作者简介:余艺华, 男, 27岁, 博士研究生.
  • 基金资助:

    国家自然科学基金

The Preparation of a Novel Adsorbent for Triglyceride and Its Adsorption Properties for Triglyceride in Serum

YU Yi-Hua1, SUN Jun-Tan1, HE Bing-Lin1, GU Han-Qing2   

  1. 1. Institute of Polymer Chemistry, The State Key Laboratory of Functional Polymer Materials forAdsorption and Separation, Nankai University, Tianjin 300071;
    2. Tianjin Institute of Urological Surgery, Tianjin 300211
  • Received:1996-07-09 Online:1997-10-24 Published:1997-10-24

摘要: 合成了一种新型的甘油三酯吸附剂-磺化羟乙基化交联壳聚糖,用其对血浆中甘油三酯进行吸附.实验结果表明,该吸附剂最高可使血清中的甘油三酯降低76.9%(每克树脂吸附量为6.25mg),而对血清中总蛋白(TP)的吸附较少.

关键词: 磺化羟乙基化交联壳聚糖, 甘油三酯, 血清, 总蛋白, 高甘油三酯血症

Abstract: Sulfonated hydroxyethylated crosslinked chitosan beads, which can selectively adsorb triglyceride, were prepared by the reaction of hydroxyethylated crosslinked chitosan and ClSO3H, using DMFas solvent. Adsorption experiments were performed by adding thebeads to the serum. The results showed that this type of adsorbent could cut down the concentration of triglyceride in plasma by 76. 9% at most, while the concentration of total protein(TP) decreased only by 2. 6% at least, so this novel adsorbent can be expected to be used for curing hypertriglyceridemia in the future.

Key words: Sulfonated hydroxyethylated crosslinked chitosan, Triglyceride, Serum, Total protein(TP), Hypertriglyceridemia

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