高等学校化学学报

高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (8): 1066.

• 论文 • 上一篇    下一篇

2,4-二羟基苯甲醛缩氨基硫脲合Cu(Ⅱ)、Zn(Ⅱ)、Ni(Ⅱ)、Fe(Ⅱ)的合成和表征及杀菌活性

祝心德, 乐芝凤, 吴自慎, 严振寰, 王成刚   

  1. 华中师范大学化学系, 武汉, 430071
  • 收稿日期:1990-03-27 出版日期:1991-08-24 发布日期:1991-08-24
  • 通讯作者: 祝心德
  • 基金资助:

    国家自然科学基金

Synthesis, Characterization and Antifungal Activity of 2,4-Dihydroxybcnzaldehyde Thiosemicarbazone and Their Complexes of Cu(Ⅱ),Zn(Ⅱ),Ni(Ⅱ)and Fe(Ⅱ)

Zhu Xin-de, Luo Zhi-feng, Wu Zi-shen, Yan Zhen-huan, Wang Cheng-gang   

  1. Department of Chemistry, Central China formal University, Wuhan, 430071
  • Received:1990-03-27 Online:1991-08-24 Published:1991-08-24

PDF (PC)

被引次数

46

摘要： 氨基硫脲类配合物具有显著的药理作用,我们合成了2,4-二羟基苯甲醛缩氨基硫脲与Cu、Ni、Zn、Fe形成的配合物,对产物进行了元素分析和多种光谱的图谱解析,推断出它们的组成和配位状态,还进行了超氧自由基的抑制率实验及杀菌活性研究。

关键词: 2, 4-二羟基苯甲醛缩氨基硫脲, 自由基, 杀菌活性

Abstract: 2, 4-Dihydroxybenzaldehyde thiosemicarbazone and their complexes of copper (Ⅱ), zinc (Ⅱ), nickel(Ⅱ) and iron(Ⅱ) were synthesized by an improved synthetic method and characterized by elemental analysis, IR, 1HNMR, MS and Mossbauer measurement. The compositions and coordination state of these compounds were established and their antifungal activity and free radical inhibition rate were also tested.

Key words: 2,4-Dihydroxybenzaldehyde thiosemicarbazone, Free radical, Antifungal activity

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