高等学校化学学报

高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (8): 1069.

• 论文 • 上一篇    下一篇

酰氨基硫脲及其相关杂环衍生物的研究(ⅩⅧ)--5-[5-(3-吡啶)-四唑-2-亚甲基]-2-芳氨基-1,3,4-噻二唑的合成及其抗菌活性

陈立民, 武和平, 张自义   

  1. 兰州大学化学系, 兰州, 730000
  • 收稿日期:1990-04-12 出版日期:1991-08-24 发布日期:1991-08-24
  • 通讯作者: 张自义

Studies on Acylthiosemicarbazides and Related Heterocyclic Derivatives (XⅧ)--Syntheses and Antibacterial Activity of 2-Arylamino-5-[5-(3-Pyridyl)-2H-tetrazol-2-ylmethylene)-1,3,4-Thiadiazoles

Chen Li-min, Wu He-ping, Zhang Zi-yi   

  1. Department of Chemistry, Lanzhou University, Lanzhou, 730000
  • Received:1990-04-12 Online:1991-08-24 Published:1991-08-24

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摘要： 四唑和噻二唑类衍生物具有广泛的生物活性,如抗真菌、抗霉菌、抗肿瘤、抗结核菌,以及促进植物生长等活性,1,4-二取代酰氨基硫脲是合成此类物质的重要原料,为了深入研究同一分子中聚结各种杂环化合物的合成及生物活性。

关键词: 杂环, 酰氨基硫脲, 1, 3, 4-噻二唑

Abstract: Syntheses of ten 5-[5-(3-pyridyl)-2H-tetrazol-2-yImethylene]-2-arylamino-1 ,3,4-thiadi-azoles(2a-i) were described with a view to studying their biological properties. The structures of these compounds were characterized by eleme nalysis,IR,1HNMR and MS.

Key words: Heterocycle, Acylthiosen rbazides, 1,3,4-Thiadiazoles

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