高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (11): 1483.

• 论文 • 上一篇    下一篇

(+)-1R,3R,5S-1,8,8-三甲基-3-甲硫基-3-氧代-2,4,3-二氮磷杂二环[3,2,1]辛烷的合成、晶体结构和分子的绝对构型

刘小兰1, 缪方明1, 刘立建2, 陈茹玉2   

  1. 1. 天津师范大学化学系, 天津, 300074;
    2. 南开大学元素有机化学研究所
  • 收稿日期:1990-04-14 出版日期:1991-11-24 发布日期:1991-11-24
  • 通讯作者: 缪方明

Synthesis, Crystal Structure and Absolute Configuration of (+)-1R,3R,5S-1,8,8-Trimethyl-3-Methylthio-3-Oxo-2,4,3-diaza-Phosphabicyclo[3,2,1] Octane

Liu Xiao-Ian1, Miao Fang-ming1, Liu Li-jian2, Chen Ru-yu2   

  1. 1. Department of Chemistry, Tianjin Normal University, Tianjin, 300074;
    2. Institute of Elemento-Organic ChemLitry, Nankai University, Tianjin
  • Received:1990-04-14 Online:1991-11-24 Published:1991-11-24

摘要: 合成标题化合物的结构经X射线分析,其晶体空间群为P21,晶胞参数a=0.7566(1)、b=0.7708(2)、c=1.0255(1)nm,β=98.60(1)°,Z=2.分子骨架由磷、氮船式七元环组成,P-S键为e键,P-O键为a键。分子绝对构型根据分子中P、S原子对CuKa射线的反常散射效应确定。

关键词: 二氮磷杂二环[3, 2, 1]辛烷, 合成, 晶体结构, 绝对构型

Abstract: The title compound was synthesized and its molecular structure was determined by X-ray diffraction analysis with Cu Ka radiation. The crystal belongs to space group P21 and the crystal cell parameters are:α=0. 7566(1) nm, b=0. 7708(2) nm, c=1. 0255(1) nm,β=98. 60(1)°, V=0. 5913 nm3, Z=2. The molecular skeleton is composed of three rings, the sev-en-membered ring containing phosphorous and nitrogen atoms in boat conformation, in which the bond P-Sis in equatorial and P-Oin axial position; the six-membered ring and five-mem-bered ring are in chair form and envelop form, respectively. The absolute configuration was established by using the approciable anomalous scattering effect of Pand Satoms.

Key words: Diazaphosphabicyclo[3,2,1]octane, Synthesis, Crystal structure, Absolute configu-ration

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