Fabricating Polysaccharide Micro-hydrogel via Superhydrophobic Pillar-structured Si Substrate †

doi:10.7503/cjcu20200193

Abstract

Abstract:

We have demonstrated a novel method for fabricating polysaccharide micro-hydrogel(PsMH) with uniform sizes. Microdroplets were adhered to micro-pillars and UV-cured during droplets evaporation to fabricate bread-like PsMH with uniform micrometer scale sizes via super-hydrophobic, high-adhesion micro-sized cylindrical structure silicon substrate. Results show that the PsMH with narrow size distributes uniformly on the top of the micro-pillars. The sizes and structure of PsMH can be effectively adjusted via polymer concentration and the diameter of micro-pillars. This polysaccharide-based microgel is expected to be used in drug delivery, nanoparticles carrier and other aspects.

Key words: Polysaccharide hydrogel, Micro-pillar, Micro-hydrogel, Super-hydrophobic pillar-structured substrate

CLC Number:

O636
O647

TrendMD:

BAO Han, LUO Jing, SHI Lianxin, XU Fujian, WANG Shutao. Fabricating Polysaccharide Micro-hydrogel via Superhydrophobic Pillar-structured Si Substrate ^†[J]. Chem. J. Chinese Universities, 2020, 41(7): 1484.

Figures/Tables 10

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d/μm	V/μm³	m_10%/pg	m_20%/pg	m_30%/pg	m_40%/pg	d_10%/μm	d_20%/μm	d_30%/μm	d_40%/μm
3.0	11.5	0.12	0.23	0.35	0.46	0	0	1.1±0.1	1.0±0.1
6.0	92.1	0.92	1.84	2.76	3.68	0	1.5±0.3	2.1±0.2	2.6±0.3
9.0	310.9	3.11	6.22	9.33	12.43	2.0±0.2	2.9±0.2	3.6±0.3	4.0±0.3
12.0	736.9	7.37	14.74	22.11	29.47	4.4±0.4	5.4±0.4	6.3±0.2	6.8±0.3
15.0	1439.2	14.39	28.78	43.18	57.57	6.2±0.4	6.6±0.3	8.1±0.4	8. 9±0. 5

d/μm	V/μm³	m_10%/pg	m_20%/pg	m_30%/pg	m_40%/pg	d_10%/μm	d_20%/μm	d_30%/μm	d_40%/μm
3.0	11.5	0.12	0.23	0.35	0.46	0	0	1.1±0.1	1.0±0.1
6.0	92.1	0.92	1.84	2.76	3.68	0	1.5±0.3	2.1±0.2	2.6±0.3
9.0	310.9	3.11	6.22	9.33	12.43	2.0±0.2	2.9±0.2	3.6±0.3	4.0±0.3
12.0	736.9	7.37	14.74	22.11	29.47	4.4±0.4	5.4±0.4	6.3±0.2	6.8±0.3
15.0	1439.2	14.39	28.78	43.18	57.57	6.2±0.4	6.6±0.3	8.1±0.4	8. 9±0. 5