Chem. J. Chinese Universities ›› 2020, Vol. 41 ›› Issue (7): 1484.doi: 10.7503/cjcu20200193

• Articles • Previous Articles     Next Articles

Fabricating Polysaccharide Micro-hydrogel via Superhydrophobic Pillar-structured Si Substrate

BAO Han1,2,LUO Jing2,SHI Lianxin2,XU Fujian1,*(),WANG Shutao2,*()   

  1. 1. Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China
    2. CAS Key Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China
  • Received:2020-04-08 Online:2020-07-10 Published:2020-06-08
  • Contact: XU Fujian,WANG Shutao E-mail:xufj@mail.buct.edu.cn;stwang@mail.ipc.ac.cn
  • Supported by:
    † National Natural Science Foundation of China(21972155);National Program for Special Support of Eminent Professionals, China

Abstract:

We have demonstrated a novel method for fabricating polysaccharide micro-hydrogel(PsMH) with uniform sizes. Microdroplets were adhered to micro-pillars and UV-cured during droplets evaporation to fabricate bread-like PsMH with uniform micrometer scale sizes via super-hydrophobic, high-adhesion micro-sized cylindrical structure silicon substrate. Results show that the PsMH with narrow size distributes uniformly on the top of the micro-pillars. The sizes and structure of PsMH can be effectively adjusted via polymer concentration and the diameter of micro-pillars. This polysaccharide-based microgel is expected to be used in drug delivery, nanoparticles carrier and other aspects.

Key words: Polysaccharide hydrogel, Micro-pillar, Micro-hydrogel, Super-hydrophobic pillar-structured substrate

CLC Number: 

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