Electrospray Ionization Mass Spectrometry Studies of Tetramolecular i-Motif Structures Formed by d(C4) Related Sequences

Chem. J. Chinese Universities ›› 2011, Vol. 32 ›› Issue (12): 2748.

• Articles • Previous Articles Next Articles

Electrospray Ionization Mass Spectrometry Studies of Tetramolecular i-Motif Structures Formed by d(C4) Related Sequences

QIN Yu-Jiao¹, WEI Shi-Gang¹, WANG Xiao-Lu¹, YANG Fan², WANG Bing¹, GUO Xin-Hua^1*

1. College of Chemistry, Jilin University, Changchun 130012, China;
2. Songliao River Basin Water Resource Protection Bureau, Changchun 130021, China

Received:2011-06-24 Revised:2011-08-17 Online:2011-12-10 Published:2011-11-25
Contact: GUO Xin-Hua E-mail:guoxh@jlu.edu.cn
Supported by:
国家自然科学基金(批准号： 20575066, 20975044)资助.

Abstract

Abstract: A series of cytosine-rich DNA sequence d(C4) related DNA strands, including d(C4), d(TC4), d(AC4), d(T2C4), d(A2C4), d(C4T), d(C4A) and d(TC4T), was designed in this study, and the tetramolecular ions formed by the sequences were measured with electrospray ionization mass spectrometry. The goal is to obtain the information on the formation of the tetramolecular i-motif influenced by adenine(A) and thymine(T) that present at 5' and 3' ends of d(C4). The results showed that when A base or T base was added at 5' end of d(C4), it is easier for the sequence to form tetramolecular ion, especially for thymine, when adding two A or T bases to d(C4), the sequence generates higher abundant of the tetramolecualr ion.

Key words: DNA i-motif structure, Electrospray ionization mass spectrometry, d(C4) related sequence, Non-covalent interaction

CLC Number:

0657.6

TrendMD:

QIN Yu-Jiao, WEI Shi-Gang, WANG Xiao-Lu, YANG Fan, WANG Bing, GUO Xin-Hua*. Electrospray Ionization Mass Spectrometry Studies of Tetramolecular i-Motif Structures Formed by d(C4) Related Sequences[J]. Chem. J. Chinese Universities, 2011, 32(12): 2748.

[1]	DENG Jiewei, YANG Yunyun, LIN Li, LUAN Tiangang. Rapid Classification of Daphniamagna and Daphnia pulex by Surface-coated Probe Nanoelectrospray Ionization Mass Spectrometry Lipidomics [J]. Chem. J. Chinese Universities, 2020, 41(9): 2011.
[2]	LI Xiaoqian, ZHANG Hua, LU Haijian, LIU Chang, LIU Qinglong, MA Xiayu, FANG Yuanping, LIANG Dapeng. Mechanism of Photocatalytic Degradation of Rhodamine B by TiO₂ Nanowire Array with Internal Extraction Electrospray Ionization Mass Spectrometry [J]. Chem. J. Chinese Universities, 2020, 41(9): 2003.
[3]	WANG Xiaoqun, HUANG Guangming. Investigation of Lipid Distributions by Trifluoroacetic Acid-enhanced Desorption Electrospray Ionization Mass Spectrometry Imaging [J]. Chem. J. Chinese Universities, 2020, 41(12): 2673.
[4]	LI Cheng,WANG Chengjian,JIN Wanjun,HAN Jianli,YANG Meifang,GAO Xi,HUANG Linjuan,WANG Zhongfu. Mass Spectrometric Analysis of N-Glycans of Glycoprotein Separated by SDS-PAGE Gel from Ginkgo Seed^† [J]. Chem. J. Chinese Universities, 2019, 40(1): 69.
[5]	WU Fangling,CHU Yanqiu,CHEN Xin,WEI Wanghui,DING Chuanfan. Critical Factors Affecting Noncovalent Interaction Between Pentapeptides Explored by Electrospray Ionization Mass Spectrometry^† [J]. Chem. J. Chinese Universities, 2018, 39(9): 1927.
[6]	KE Mufang, HAN Jing, ZHU Tenggao, LIU Wenjie, ZHANG Hua, KOU Wei, LIANG Dapeng. Direct and Rapid Analysis of Avocado Using Internal Extractive Electrospray Ionization Mass Spectrometry^† [J]. Chem. J. Chinese Universities, 2017, 38(5): 738.
[7]	HUANG Yandong, WU Ruofei, CHU Yanqiu, DING Chuanfan. Effect of Side Chain of α-Amino Acids and Esters on the Stability Constants for β-Cyclodextrin Complexes^† [J]. Chem. J. Chinese Universities, 2017, 38(5): 743.
[8]	PENG Yifang, WANG Chengjian, WANG Jingjing, LI Lingmei, JIN Wanjun, QIANG Shan, SHI Hongdan, ZHANG Ying, HUANG Linjuan, WANG Zhongfu. Analysis of Antigenic Determinant Glycans of Peanut Allergy Glycoprotein Ara h1 by Mass Spectrometry^† [J]. Chem. J. Chinese Universities, 2016, 37(9): 1622.
[9]	LI Penghui, DENG Lingli, LUO Jiao, LI Wei, NING Jing, DING Jianhua, WU Xiaoping. EESI-MS Detection and Statistical Analysis of Multi-batch of Exhaled Breath Metabolomics Data of Liver Failure Patients [J]. Chem. J. Chinese Universities, 2016, 37(4): 626.
[10]	WU Ruofei, CHU Yanqiu, XU Chongsheng, LIU Zhipan, DING Chuanfan. Fragmentation Reaction of Complexes of Alkali Metal Cations with Tripeptides in Gas Phase^† [J]. Chem. J. Chinese Universities, 2016, 37(12): 2150.
[11]	CHEN Huanhuan, ZHAO Xia, LUAN Xiaohong, YU Guangli. Application of Electrospray Tandem Mass Spectrometry in Sequence Analysis of Oligosaccharides^† [J]. Chem. J. Chinese Universities, 2015, 36(1): 1.
[12]	DAI Yulin, YU Shanshan, ZHANG Ying, HAO Ying, ZHONG Wei, YUE Hao, LIU Shuying. Studies on the Isoflavone in Extract of the Flower of Pueraria Lobata by RRLC-Q-TOF MS/MS^† [J]. Chem. J. Chinese Universities, 2014, 35(7): 1396.
[13]	FANG Feifei, DU Shangguang, DAI Ximo, GUO Xiali, CHEN Huanwen, LUO Liping. Rapid Analysis Alkaloids in Lotus Seeds by Extractive Electrospray Ionization Mass Spectrometry^† [J]. Chem. J. Chinese Universities, 2014, 35(4): 730.
[14]	PAN Liying, WANG Chengjian, YUAN Jiangbei, ZHANG Ying, HUANG Linjuan, WANG Zhongfu. Qualitation and Quantitation for Comparative Analysis of N-glycans from Human Hepatocellular Carcinoma HepG2 and Normal Liver Cells L02 by Electrospray Ionization Mass Spectrometry^† [J]. Chem. J. Chinese Universities, 2014, 35(2): 237.
[15]	LIN Mei-Na, ZHANG Wei-Ying, LI Xiao, YING Xiao-Guang, CHEN Shuang-Shuang. Non-covalent Interaction of Tryptophan with Functional Monomers in Self-assembly Systems [J]. Chem. J. Chinese Universities, 2013, 34(1): 198.

Electrospray Ionization Mass Spectrometry Studies of Tetramolecular i-Motif Structures Formed by d(C4) Related Sequences

PDF (PC)

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments