Chem. J. Chinese Universities ›› 2004, Vol. 25 ›› Issue (5): 982.

• Articles • Previous Articles     Next Articles

Application of Quantum Dots Labeling to the Interaction Between Reconstructed-phage Display Peptide and Insulin Receptor

LI Hong-Mei1, LIU Han-Zhi1, ZHANG Hao2, ZHU Gui-Bin3, WANG Li-Ping1, YANG Bai2, LI Wei1   

  1. 1. College of Life Science, Jilin University;
    2. College of Chemistry, Key Lab of Supramolecular Structure and Materials of Ministry of Educational, Jilin University;
    3. School of Basic Medical Sciences, Jilin University, Changchun 130023, China
  • Received:2003-10-23 Online:2004-05-24 Published:2004-05-24

Abstract: Luminescent quantum dots(QDs) are a promising alternative to organic dyes for fluorescence-based applications. Filamentous phage was labeled with QDs and its infective capability is observed after labeling. The experimental result shows that the labeling phage can still infect E.coli K91 normally. We have also developed the procedures for using QDs to label CHO-IR cells and Mouse Kidney tissue slice. The tissue slice remained stably labeled for over 10 d and the cells remained stably labeled even for over 5 months.

Key words: Quantum dot, Reconstructed-phage, Fluorescence label

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