Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (7): 1228.

• Articles • Previous Articles     Next Articles

Cd2+ Ions Induced Conformation Change of DNA

CHEN Xia, YANG Wen-Sheng, JIN Jian, XU Li, YANG Bai-Quan, JIANG Lin, LI Tie-Jin, Chen-Xi   

  1. 1. Center for Intelligent Materials United Research, Department of Chemistry, Jilin University, Changchun 130023, China;
    2. Tong hua Nursing School, Tong hua 135000, China
  • Received:2000-04-14 Online:2001-07-24 Published:2001-07-24

Abstract: Interactions between Cd 2+ ions and salmon sperm DNAwere investigated via UV-Vis, Circular Dichroism(CD) and FT-Raman spectroscopies. The experimental results show that Cd 2+ ions can coordinate with the phosphate groups of DNAand thus induce conformation changes of the DNAfrom Bto Atype.

Key words: Cd 2+ ion, DNA, Conformation, Circular dichroism

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