Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (3): 389.

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Genosensors and Strategies for the Research and Development

PANG Dai-Wen, YAN Wei   

  1. Department of Chemistry, Wuhan University, Wuhan 430072, China
  • Received:2000-04-07 Online:2001-03-24 Published:2001-03-24

Abstract: Recent featured researches on optical, piezoelectric, and electrochemical biosensors for gene detection are reviewed. Some related issues, including reliability, sensitivity, applicability, and antidisturbance, etc., involved in genosensors are discussed. And the strategies for the immobilization and characterization of gene probes, molecular hybridization on the surfaces, effective transduction of hybridization signals and related detection techniques are proposed.

Key words: DNA, Gene technique, Sensor technique, Strategy

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