Enantiomer Separation of Glycerin Sulfides and Glycerin Selenides with a Chiral Stationary Phase of Cellulose Derivative

Abstract

Abstract: Cellulose-tris(3, 5-dimethylphenylcarbamate) was prepared and immobilized onto a mesopore spherical aminopropylated silica gel.The final product was used as a chiral stationary phase for the enantioseparation of a series of glycerin sulfides and glycerin selenides.Some enantiomers of the monosulfides and monoselenides could be separated satisfactorily,but the bisulfides could not at all.The structural characteristic of the samp1es that influence chiral discrimination was disscused.The effect of 2-propanol concentration in the mobile phase on the retention and resolution was also investigated.

Key words: Cellulose derivative, Chiral stationary phase, HPLC, Enantiomer separation

CLC Number:

O658

TrendMD:

YU Zhao-Wen, LIU Kuai-Zhi, JIANG Sheng-Xiang, CHEN Li-Ren. Enantiomer Separation of Glycerin Sulfides and Glycerin Selenides with a Chiral Stationary Phase of Cellulose Derivative[J]. Chem. J. Chinese Universities, 1999, 20(9): 1376.

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Enantiomer Separation of Glycerin Sulfides and Glycerin Selenides with a Chiral Stationary Phase of Cellulose Derivative

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