Studies on the Application of Spline Least Square Method to Capillary Electrophoresis

Abstract

Abstract: The Spline Least Square Method(SLSM) was applied to deal with the capillary electrophoresis graph containing a strong white nosie. The mathematical principle of SLSMwas introduced and the parameters, spline order k and filter length L, which affect the results directly, were discussed. Acapillary electrophoresis system with amperometric detector, micro Pt electrode as the working electrode, was demonstrated by running several phenols compounds in 50 μm×75 cm capillary. It shows SLSMhas a great applicability to handle complex graph with a strong white noise, and can give acceptable result even if the niose is as strong as the signal.

Key words: Spline function, Spline least square method, Capillary electrophoresis, Data processing

CLC Number:

O651

TrendMD:

XIE Tian-Yao, MO Jin-Yuan, YANG Xiao-Yun . Studies on the Application of Spline Least Square Method to Capillary Electrophoresis[J]. Chem. J. Chinese Universities, 1998, 19(12): 1940.

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Studies on the Application of Spline Least Square Method to Capillary Electrophoresis

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