Studies on Synthesis and Fungicidal Activity of S-Alkyl-O-(2, 6-dichloro-4-substituted phenyl)Thiophosphates (-phosphonates)

Abstract

Abstract: S-Alkyl thiophosphoro (-phosphono-)chloridates 4 were prepared by the isomer-ization/chlorination reaction of O,O-dialkyl thiophosphates(-phosphonates)3 with phospho-rus oxychloride- The isomerization/chlorination of 3 containing bulkier Rand R¹ groups re-quire higher reaction temperatures and Ionger reaction time.4 reacted with 2, 6-dichloro-4-substituted phenols to give 26 new target compounds 6, which were tested in vitro against many fungi such as P.Zeae, P.Piricola, R.Solani, A- Solani and D.Arachidicala, etc.The bioassay results show they have some fungicidal activity.

Key words: Isomerization, Chlorination, Thiophosphates, Fungicidal activity

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TANGChu-Chi, WANG You-Ming, LANG Hui-Fang, HE Zheng-Jie . Studies on Synthesis and Fungicidal Activity of S-Alkyl-O-(2, 6-dichloro-4-substituted phenyl)Thiophosphates (-phosphonates)[J]. Chem. J. Chinese Universities, 1997, 18(1): 55.

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Studies on Synthesis and Fungicidal Activity of S-Alkyl-O-(2, 6-dichloro-4-substituted phenyl)Thiophosphates (-phosphonates)

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