Novel Glutathione Photoelectrochemical Sensor Based on PbS QDs/TiO2 NPs †

doi:10.7503/cjcu20190106

Abstract

Abstract:

Firstly, titanium dioxide nanoparticles(TiO₂ NPs) was modified to the surface of indium tin oxide(ITO) electrode by high-temperature calcination to prepare TiO₂ NPs/ITO electrode. And then sulfide quantum dots(PbS QDs) were modified to the surface of TiO₂ NPs/ITO electrode by successive ionic layer adsorption and reaction(SILAR) cycle to prepare the PbS QDs/TiO₂ NPs/ITO electrode. And it was used to detect glutathione(GSH). In this sensor, when PbS QDs are excited by 470 nm visible light, it will produce electrons(e) and holes(h ⁺). Immediately after, h ⁺ will be captured by GSH in solution, and then GSH is oxidized into GSSH. Therefore, the recombination of electrons and holes were avoided effectively. Thus the photoelectric efficiency has been significantly improved. This sensor had satisfactory sensitivity and selectivity for GSH. what’s more, the detection range is 0.06—1 mmol/L, and the detection limit(LOD) is 4.6×10 ^-3 mmol/L(S/N=3).

Key words: PbS QDs, TiO₂ NPs, Glutathione(GSH), Photoelectrochemical, Biosensor

CLC Number:

O652.1

TrendMD:

ZHENG Shan, LIU Yang, CHEN Piaopiao, XING Yichen, HUANG Chaobiao. Novel Glutathione Photoelectrochemical Sensor Based on PbS QDs/TiO₂ NPs ^†[J]. Chem. J. Chinese Universities, 2019, 40(9): 1866.

Figures/Tables 13

Fig.1 SEM images of TiO2 NPs/ITO(A) and PbS QDs/TiO2 NPs/ITO(B) electrodes

Fig.2 XRD patterns of ITO(a), TiO2 NPs/ITO(b) and PbS QDs/TiO2 NPs/ITO(c) electrodes

Fig.3 Full-scan XPS spectra of TiO2 NPs and PbS QDs/TiO2 NPs electrodes(A) and high-resolution XPS spectra of Ti2p(B), O1s(C), Pb4f(D) and S2p(E) of PbS QDs/TiO2 NPs electrode

Fig.4 EIS of TiO2 NPs/ITO(a) and PbS QDs/TiO2 NPs/ITO(b) electrodes The EIS measurements are carried out in 0.1 mol/L KCl containing 5.0 mmol/L K3Fe(CN)6/K4Fe(CN)6(1∶1), The frequency range was between 0.1 and 1×105 Hz with an applied voltage of 5 mV. Inset: equivalent circuit diagram. Cd: capacitance; Rct: charge transfer resistance; Ru: ohmic resistance; Zw: diffusion resistance.

Fig.5 Effect of TiO2 NPs concentration on photocurrent responses of the sensor

Fig.6 Effect of SILAR cycle times on photocurrent responses of the sensor

Fig.7 Effect of wavelength on photocurrent responses of the sensor

Fig.8 Effect of potential on photocurrent responses of the sensor

Fig.9 Photocurrent response curves of different modified ITO(a), TiO2/ITO(b), PbS QDs/TiO2/ITO(c) and QDs/TiO2/ITO(d) electrodes in 0.2 mmol/L GSH/PbS

Fig.10 Preparation process diagram(A) and mechanism diagram(B) of GSH sensor

Fig.11 Linear calibration curve GSH sensor Inset: Photocurrent response of GSH sensor.

Fig.12 Stability of PbS QDs/TiO2 NPs/ITO electrode

Fig.13 Photocurrent signals of the GSH sensor toward in the presence of 1 mmol/L cysteine(Cys), alanine(Ala), dopamine(DA), glycine(Gly), leucine(Lue), arginine(Arg), valine(Val), glucose(Glu) and all their mixture(Mix) and 0.2 mmol/L GSH

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Novel Glutathione Photoelectrochemical Sensor Based on PbS QDs/TiO₂ NPs ^†

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