Synthesis of Dipicolinate Sensitized LaF3∶Tb Nanoparticles and Their Application in the Determination of DNA

doi:10.7503/cjcu20121051

Abstract

Abstract:

Lanthanide nanoparticles have been used in bioanalysis due to their excellent luminescence properties. Herein, dipicolinate(DPA) sensitized LaF₃:Tb(DPA-LaF₃:Tb) nanoparticles with good water solubility were synthesized by hydrothermal method, which emit strong and stable luminescence. X-Ray diffraction(XRD) pattern showed that the particles were single-phase LaF₃ crystals in hexagonal system, and transmission electron microscopy(TEM) image showed a good dispersion of DPA-LaF₃:Tb nanoparticles with nearly uniform size of about 15 nm. The lifetime of the particles in water was measured 2.95 ms. It was found that DNA could quench effectively the luminescence of the particles. Based on the luminescence quench, the determination of DNA was realized with the linear range of 0.083~13.0 μg/mL and the detection limit of 0.02 μg/mL. Moreover, the interference of coexistence substances to the determination of DNA was studied.

Key words: Luminescence, Lanthanide nanoparticles, Dipicolinate, DNA, LaF₃∶Tb

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YU Yong-Li, WANG Li-Mei, XU Shu-Kun, ZHANG Xiu-Juan. Synthesis of Dipicolinate Sensitized LaF₃∶Tb Nanoparticles and Their Application in the Determination of DNA[J]. Chem. J. Chinese Universities, 2013, 34(7): 1617.

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Synthesis of Dipicolinate Sensitized LaF₃∶Tb Nanoparticles and Their Application in the Determination of DNA

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