Effects of Microstructure of Calcium Phosphate Ceramics Particles on Protein Adsorption

doi:10.3969/j.issn.0251-0790.2012.03.003

Abstract

Abstract:

To investigate the effects of physical and chemical properties of nano calcium phosphate ceramics on protein adsorption, two types of nano calcium phosphate particles and two kinds of micron ones were prepared with microwave sintering method and conventional method, respectively. The phase compositions, surface morphologies, particle size distribution, specific surface area, pore size distribution and zeta potentials of four particles were analyzed with X-ray diffraction, scanning electron microscope, dynamic laser system, BET method and zetasizer. Bovine serum album(BSA) and lysozyme(LSZ) adsorbed on ceramics were further investigated by polyacrylamide gel electrophoresis method. The results show that nano and conventional ceramics have similar phase compositions, particle size distribution and zeta potentials. Owing to smaller grain size and more abundant mesoporous structure, nano ceramics adsorb more BSA and LSZ than conventional ones.

Key words: Calcium phosphate ceramics, Micro/nano-structure, Microwave, Protein adsorption

CLC Number:

O614.23
R318

TrendMD:

LI Bo, ZHANG Hui-Jie, LIAO Xiao-Ling, ZHU Xiang-Dong, FAN Hong-Song, ZHANG Xing-Dong. Effects of Microstructure of Calcium Phosphate Ceramics Particles on Protein Adsorption[J]. Chem. J. Chinese Universities, 2012, 33(03): 447.

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