Chem. J. Chinese Universities ›› 2019, Vol. 40 ›› Issue (8): 1579.doi: 10.7503/cjcu20190076

• Articles: Inorganic Chemistry • Previous Articles     Next Articles

Microwave-assisted Hydrothermal Synthesis of Carbon Dots Based on Tyrosine and Their Application in Ion Detection and Bioimaging

HUANG He, LI Chunguang, SHI Zhan, FENG Shouhua   

  1. State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012, China
  • Received:2019-01-23 Revised:2019-07-23 Online:2019-08-10 Published:2019-07-12
  • Supported by:
    Supported by the National Natural Science Foundation of China(Nos. 21771077, 21771084, 21621001), the National Key Research and Development Program of China(No. 2016YFB0701100), the "111" Project of China(No. B17020) and the Program for JLU Science and Tech-nology Innovative Research Team, China.

Abstract: Cabon dots(CDs) were synthesized utilizing tyrosine as carbon source, ethanediamine as passivant through a green microwave-assisted hydrothermal way. The size of CDs can be adjusted by the dose of ethanediamine. The as-prepared CDs have uniform size and good dispersibility, showing blue or green fluorescence. The as-prepared CDs can change their fluorescence(from blue to yellow) by changing the excitation light and the emission light can be kept without large decay. The as-synthesized CDs have good selectivity on the detection of Fe3+ with a limit of detection(LOD) of 0.82 nmol/L, and a detection limit of 2.98 nmol/L. The as-synthesized CDs also have great biocompatibility and low biotoxicity, and can be utilized as a probe to label AD293 cells, marking the cytoplasm of the cells.

Key words: Carbon dot, Microwave-assisted hydrothermal method, Fe3+ detection, Biomarking

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