高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (2): 209.

• 研究论文 • 上一篇    下一篇

矿物药炉甘石成分分析及其纳米形态的抑菌活性研究

郭义明, 赵敬哲, 于开锋, 刘艳华, 王子忱, 张恒彬   

  1. 吉林大学化学学院, 长春 130023
  • 收稿日期:2004-01-05 出版日期:2005-02-10 发布日期:2005-02-10
  • 通讯作者: 王子忱(1953年出生),男,博士,教授,博士生导师,从事功能材料物理化学研究.E-mail:wangzc@mai.ljlu.edu.cn E-mail:wangzc@mai.ljlu.edu.cn
  • 基金资助:

    吉林省科学技术发展计划项目(批准号:20020659)资助

Components Analysis and Antibacterial Activity of Calamine

GUO Yi-Ming, ZHAO Jing-Zhe, YU Kai-Feng, LIU Yan-Hua, WANG Zi-Chen, ZHANG Heng-Bin   

  1. College of Chemistry, Jilin University, Changchun 130023, China
  • Received:2004-01-05 Online:2005-02-10 Published:2005-02-10

摘要: 用差示热重等方法分析了矿物中药炉甘石的成分,合成纳米碱式碳酸锌和纳米氧化锌,制备了纳米炉甘石.用激光粒度分析仪测定了炉甘石及其成分的粒径分布,用透射电镜观察纳米氧化锌的形貌.采用杯碟法,以四环素为对照品,测试纳米炉甘石及其成分的抑菌活性.结果显示,氧化锌的含量与粒径大小决定了炉甘石的抑菌活性,纳米炉甘石抑菌活性显著提高.

关键词: 纳米炉甘石, 碱式碳酸锌, 氧化锌, 抑菌活性

Abstract: The components of traditional Chinese medicine calamine were determined with thermogravimetric analysis method and otherwise. Nanosized zinc carbonate alkali and nanosized zinc oxide were synthesized, and nanosized calamine was prepared. The particle size and morphology of calamine, zinc carbonate alkali and zinc oxide were determined by laser size analysis device and transmission electron microscope(TEM). The antibacterial activity of calamine and its components were determined by using beaker disc method. The result shows that the antibacterial activity of calamine was decided by the content and particle size of zinc oxide, and the antibacterial activity of nanosized calamine was better than that of calamine. Nanosized calamine possesses the characters of calamine and nanosized traditional Chinese medicine, and it has the double activities of calamine and nanoparticles. Zinc carbonate alkali and nanosized zinc carbonate alkali have not antibacterial activity for the four bacteria in this paper.

Key words: Nanosized calamine, Zinc carbonate alkali, Zinc oxide, Antibacterial activity

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