高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (10): 1820-1824.

• 研究论文 • 上一篇    下一篇

杯芳烃衍生物和丙烯酰胺作为复合功能单体的分子印迹聚合物对海因类化合物的选择性识别研究

卢春阳1, 王华芳1, 何锡文1, 陈朗星1, 李文友1, 曾宪顺1, 张玉奎1,2   

  1. 1. 南开大学化学系,元素有机化学国家重点实验室,天津300071;
    2. 中国科学院大连化学物理研究所,大连116011
  • 收稿日期:2004-09-29 出版日期:2005-10-10 发布日期:2005-10-10
  • 基金资助:

    国家自然科学基金(批准号:20375017,20375019,20445001);高等学校博士学科点专项科研基金(批准号:2002055002);天津市自然科学基金(批准号:033603511)资助.

Molecularly Imprinted Polymer with Bi-functional Monomers of Calix Arene Derivative and Acrylamide for Selective Recognition of Hydantoin-based Compounds

LU Chun-Yang1, WANG Hua-Fang1, HE Xi-Wen1, CHEN Lang-Xing1, LI Wen-You1, ZENG Xian-Shun1, ZHANG Yu-Kui1,2   

  1. 1. Department of Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University, Tianjin 300071,China;
    2. Dalian Institute of Chemical Physics,Dalian 116011,China
  • Received:2004-09-29 Online:2005-10-10 Published:2005-10-10

摘要: 以杯[4]芳烃衍生物+丙烯酰胺作为复合功能单体,将其运用到分子印迹技术中,对海因类化合物R-苄基海因进行选择性识别.研究结果表明,由单一的杯[4]芳烃衍生物或丙烯酰胺作为功能单体的分子印迹聚合物对R-苄基海因的选择性均不高,而由杯[4]芳烃衍生物+丙烯酰胺作为复合功能单体的分子印迹聚合物对模板分子具有较高的特异选择性.

关键词: 分子印迹技术, 双功能单体, 杯芳烃衍生物, 丙烯酰胺, 海因类化合物

Abstract: Using calix[4]arene derivative and acrylamide(AM) as the bi-functional monomers and 5-benzylhydantoin(R-BZH) as a template,a molecularly imprinted polymer was prepared to recognize hydantoin-based compounds selectively.The results of equilibrium binding experiments indicate that the selectivity of the MIP,which is synthesized with a single functional monomer(calix[4]arene derivative or acrylamide),is poor;while the selectivity of another MIP,which is synthesized with two functional monomers(both calix[4]arene derivative and AM),showed higher and better selective recognition abilities for R-BZH. It was entirely possible to separate and enrich R-BZH from hydantoin-based compounds by molecularly imprinting technique.

Key words: Molecularly imprinted technique, Bi-functional monomers, Calix[4]arene derivative, Acrylamide, Hydantoin-based compound

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