高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (9): 1408.

• 研究简报 • 上一篇    下一篇

光活性1,1'-联萘酚(BINOL)的不对称合成

粟武, 王恒山, 达朝山, 王锐   

  1. 兰州大学生命科学学院, 应用有机化学国家重点实验室, 兰州 730000
  • 收稿日期:1999-10-11 出版日期:2000-09-24 发布日期:2000-09-24
  • 通讯作者: 王　锐(1963年出生),男,博士,教授,博士生导师,主要从事不对称合成研究.
  • 基金资助:

    国家自然科学基金(批准号:29972016);甘肃省自然科学基金(批准号:Zs991-A23-056Y)资助

Asymmetric Synthesis of Optically Active1,1'-Bi-2-naphthol

SU Wu, WANG Heng-Shan, DA Chao-Shan, WANG Rui    

  1. School of Life Sciences, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
  • Received:1999-10-11 Online:2000-09-24 Published:2000-09-24

PDF (PC)

关键词: 不对称合成, 1, 1'-联萘酚, 苯乙胺

Abstract: Experimental results are reported for the CuCl2-mediated asymmetric oxidative coupling of 2-naphthols in the presence of [-]α-methylbenzylamine to optically active (S)-(-)-1,1'-bi-2-naphthol. Under anhydrous conditions and with a 3∶1 molarity ratio of α-methylbenzylamine to 2-naphthol, a fair enantioselection has been observed(up to 80.6% ee).

Key words: Asymmetric synthesis, 1,1'-Bi-2-naphthol, α-Methylbenzylamine

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