高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (8): 1254.

• 论文 • 上一篇    下一篇

单链2,7-取代萘刚性生色基双亲化合物的合成及其在稀溶液中的自组织

李国文1, 刘玺玉1, 吴立新1, 沈家骢1, 梁映秋2   

  1. 1. 吉林大学超分子结构与谱学开放实验室, 长春 130023;
    2. 南京大学化学系, 南京 210093
  • 收稿日期:1999-01-26 出版日期:1999-08-24 发布日期:1999-08-24
  • 通讯作者: 李国文,男,53岁,副教授.
  • 作者简介:李国文,男,53岁,副教授.
  • 基金资助:

    吉林省科学技术委员会基金

Synthesis of Single-chain Amphiphiles Containing 2,7-Substituted Naphthalene Rigid Segment and Self-organization of the Amphiphiles in Dilute Aqueous Solution

LI Guo-Wen1, LIU Xi-Yu1, WU Li-Xin1, SHEN Jia-Cong1, LIANG Ying-Qiu2   

  1. 1. Key Laboratory of Superamulecular Structure and Spectroscopy, Jilin University, Changchun 130023, China;
    2. Department of Chemistry, Nanjing University, Nanjing 210093, China
  • Received:1999-01-26 Online:1999-08-24 Published:1999-08-24

PDF (PC)

被引次数

2

摘要： 合成了系列单链含2,7-取代萘刚性生色基的双亲化合物CnNaph(2,7)C6N+(n=4,7,10,12,16),分别用透射电镜、1HNMR和DSC观测了该系列双亲物在稀溶液中的聚集形态,研究了聚集体内的分子运动和凝胶态到液晶态的相变.结果表明,当尾链n≥7时,该系列化合物在稀溶液中自组织成双分子层排列的囊泡,当n=4时聚集体无确定形态.

关键词: 自组织作用, 双分子膜, 囊泡, 相变

Abstract: Aseries of single-chain amphiphile containing 2,7-substituted naphthalene rigid segment, alkyl tail chain and spacer portion, CnH2n+1OC10H6O(CH2)6N+(CH3)3Br-(n=16, 12, 10, 7, 4), has been synthesized. The aggregate morphology of the amphiphiles in dilute aqueous solution was observed by electron microscopy, and found to form aggregate global-shaped vesicles with 200-400nm when n≥7 and unstable dispersion when n=4. The gel to liquid crystal phase transition of the bilayer membranes was studied by means of differential scanning calorimmetry(DSC). The molecular motion in the membranes was investigated by 1HNMR. The experiment results indicate that the amphiphiles are of practical bilayer forming, capable of organizing biomembrane mimetic agent and suggest that the vesicle structure are composed of the bilayer structure similar to that of biomembranes.

Key words: Self-organization, Bilayer membrane, Vesicles, Phase transition

中图分类号: 

TrendMD: