高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (7): 1082.

• 论文 • 上一篇    下一篇

含2-苯基-1,2,3-三唑色酮及嘧啶类化合物的合成

刘方明1, 于建新1, 王玮1, 刘育亭1, 陈耀祖2   

  1. 1. 新疆大学化学系, 乌鲁木齐, 830046;
    2. 浙江大学化学系, 杭州, 310027
  • 收稿日期:1997-05-20 出版日期:1998-07-24 发布日期:1998-07-24
  • 通讯作者: 刘方明,32岁,博士,副教授.
  • 作者简介:刘方明,32岁,博士,副教授.
  • 基金资助:

    国家自然科学基金(批准号:29702007)资助课题.

Synthesis of Some New Chromones and Pyrimidinones Containing 2-Phenyl-1,2,3-triazole

LIU Fang-Ming1, YU Jian-Xin1, WANG Mei1, LIU Yu-Ting1, CHEN Yao-Zu2   

  1. 1. Department of Chemistry, Xinjiang University, Ulumuqi, 830046;
    2. Department of Chemistry, Zhejiang University, Hangzhou, 310027
  • Received:1997-05-20 Online:1998-07-24 Published:1998-07-24

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被引次数

5

摘要： 报道了取代邻位羟基苯乙酮(Ⅰa-Ⅰe)与2-苯基-1,2,3-连三唑-4-甲酸缩合制得酚酯(Ⅱa-Ⅱe),Ⅱa-Ⅱe经重排得1,3-二酮化合物(Ⅲa-Ⅲe),Ⅲa-Ⅲe在本酸性催化条件下环化为2-位连杂环色酮(Ⅳa-Ⅳe),Ⅲa-Ⅲe分别与脲和硫脲缩合得到嘧啶酮Ⅴa-Ⅴe和Ⅵa-Ⅵe.

关键词: 色酮, 1, 2, 3-三唑, 嘧啶

Abstract: The preparation of five new 2-heterocyclic substituted chromones and of ten new related pyrimidinones is reported. Condensation of 2-hydroxy acetophenones Ⅰa-Ⅰewith 2-phenyl-1,2,3-triazole-4-carboxylic acid followed by Baker Venkataraman rearrangement led to 1,3-diketones Ⅲa-Ⅲe, which yielded chromones Ⅳa-Ⅳeon dehydration and pyrimidinones Ⅴa-Ⅴeon condensation with urea and thiourea respectively. Their structures were confirmed on the basis of elemental analysis, IR, 1HNMR and MSs pectral data.

Key words: Triazole, Chromone, Pyrimidinones

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