高等学校化学学报 ›› 1993, Vol. 14 ›› Issue (7): 966.

• 研究论文 • 上一篇    下一篇

去氧胆酸钠在水溶液中的簇集行为

江云宝, 胡劲松, 许金钩, 黄贤智   

  1. 厦门大学化学系, 厦门 361005
  • 收稿日期:1992-07-09 修回日期:1992-11-15 出版日期:1993-07-24 发布日期:1993-07-24
  • 通讯作者: 江云宝
  • 作者简介:第一作者:男, 30岁, 博士, 副教授.
  • 基金资助:

    福建省自然科学基金

Aggregation of Sodium Deoxycholate in Aqueous Solution

JIANG Yun-Bao, HU Jing-Song, XU Jin-Gou, HUANG Xian-Zhi   

  1. Department of Chemistry, Xiamen University, Xiamen, 361005
  • Received:1992-07-09 Revised:1992-11-15 Online:1993-07-24 Published:1993-07-24

摘要: 用外源荧光探针法和旋光度、电导率及pH滴定法研究了去氧胆酸钠(SDOC)在水溶液中的簇集行为.SDOC浓度低于5×10-3~6×10-3mol/L时在水溶液中以二元缔合物形式存在,具有较高的对称性和较弱的碱性并能提供一定的疏水性微环境;浓度高于该值后簇集成胶束,但簇集数(8~10)较小,同时伴随着对称性略微降低和碱性有所提高.

关键词: 簇集行为, 去氧胆酸钠, TICT荧光探针, 旋光, 电导

Abstract: The aggregation behavior of a steroidal surfactant--sodium deoxycholate (SDOC) inaqueous solution was studied by extrinsic fluorescent probe [via twisted intramolecular charge transfer (TICT) fluorescence characteristics of p-N,N-dimethylamminobenzaldehyde, DMABA], optical rotation, conductivity, and pHmeasurement.TICTfluorescence band of DMABAshifts to blue and the fluorescence intensity ratio (Ia/Ib) of TICTband to LEband increases with the increase of SDOCconcentration up to 6.0× 10-3 mol/L, then the variation trends reversed.These results indicate that the critical micelle concentration of SDOCis 6.0×10-3 mol/Land that the SDOCmolecules don't exist in monomer but in dimer which provides a hydrophobic microenvironment less polar than that of SDOCmicelle.Fittig the conductivity data of aqueous SDOCsolution yields an average aggregation number of 8-10 for SDOCmicelle which is substantially less than that of normal micelle.Optical rotation and pHmeasurements show that SDOCmicelle has a relatively lower symmetry and stronger basicity than the dimer.

Key words: Aggregation behavior, Sodium deoxycholate, TICT fluorescent probe, Optical rotation, Conductivity

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