高等学校化学学报 ›› 1993, Vol. 14 ›› Issue (12): 1677.

• 研究论文 • 上一篇    下一篇

高效液相色谱二氮杂冠醚键合相的合成及性能研究

达世禄, 何国亮, 王忠华   

  1. 武汉大学化学系, 武汉 430072
  • 收稿日期:1992-12-31 修回日期:1993-08-22 出版日期:1993-12-24 发布日期:1993-12-24
  • 通讯作者: 达世禄, 男, 53岁, 教授.
  • 作者简介:达世禄, 男, 53岁, 教授.
  • 基金资助:

    国家自然科学基金

Studies on Synthesis and Characteristics of High Performance Liquid Chromatography Bonded Pase Containing Diaza Crown Ether

DA Shi-Lu, HE Guo-Liang, WANG Zhong-Hua   

  1. Department of Chemistry, Wuhan University, Wuhan, 430072
  • Received:1992-12-31 Revised:1993-08-22 Online:1993-12-24 Published:1993-12-24

摘要: 本文报道在硅胶表面进行固-液相反应,合成硅胶键合二氮杂冠醚高效液相色谱固定相.采用有机元素分析、热分析、红外光谱、金属离子的络合容量测定等对键合材料进行鉴定和表征,并对其色谱性能进行了研究.

关键词: 高效液相色谱, 键合固定相, 二氮杂冠醚

Abstract: Anew silica gel bonded phase, propyloxy methyl-diaza-1-8-crown-6 silane bonded phase (DN18-C-6), was synthesized via solid-liquid phase three-step-reaction on the surface of prorous silica:the prorous silica gel grafting with γ-gllycidoxypropyltrimethoxysilane; the epoxy-substituted silica reacting by ethylenediamine; the reaction with polyethylene glycol ditosylate in the presence of sodium hydride as catalyst.It possessed good thermal and chemical stabilities and highly separation selectivity for aromatic amine and phenols and the components of nucleic acid.The complexation capacities of DN18-C-6 for sodium and postassium picrate, CuSO4, AgNO3, Ni(NO3)2 were determined.It showed a good ability to complex with them.

Key words: HPLC, Bonded stationary phase, Diaza crown ether

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