高等学校化学学报

高等学校化学学报 ›› 1992, Vol. 13 ›› Issue (8): 1063.

• 论文 • 上一篇    下一篇

1,3,2-氧氮磷杂环戊烷衍生物(Ⅲ)——2-取代苯氧(氨)基-1,3,2-氧氮磷杂环戊烷的合成及其性质

杨华铮, 张跃华   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1991-10-06 出版日期:1992-08-24 发布日期:1992-08-24
  • 通讯作者: 杨华铮
  • 基金资助:

    国家自然科学基金

1,3,2-Oxazaphospholidine Derivatives(Ⅲ)——Studies on Synthesis and Biological Activity of 1,3,2-OxazaphosphoIidine Derivatives

YANG Hua-Zheng, ZHANG Yue-Hua   

  1. Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071
  • Received:1991-10-06 Online:1992-08-24 Published:1992-08-24

PDF (PC)

摘要： 用三氯硫磷与β-羟基乙胺类化合物在四氢呋喃溶液中反应,再加入苯酚(胺),一锅反应合成了一系列2-取代苯氧(氨)基-1,3,2-氧氮磷杂环戊烷,并对其波谱性质进行了讨论.

关键词: 1, 3, 2-氧氮磷杂环戊烷, 三氯硫磷, &beta, -羟基乙胺

Abstract: Using THF as the solvent,a series of new 2-substituted phenoxyl(anilino)-1,3,2-ox-azaphospholidine derivatives were prepared by the reaction of phosphorus sulfochloride with ami-noethanol directly and then treating with phenol or aniline in the presence of triethylamine.This is one pot reaction without the separation and purification of any intermediate and a high yield was obtained.AHof these compounds were confirmed by 1H NMR,IR,MS and elementary analysis,Their 1H NMR,and MS spectra and biological activity are discussed.

Key words: 1,3,2-Oxazaphosphoiidine, Phosphorus sulfochloride, β-Hydroxyethylamine

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