自组装单分子层对多巴黏附能力的可控性研究

doi:10.7503/cjcu20180291

摘要/Abstract

摘要：

将端基分别带—OH和—CH₃基团的11-巯基-1-十一醇和1-十二烷基硫醇2种硫醇分子按不同摩尔比(1:0, 3:1, 1:1, 1:3和0:1)自组装到金片表面, 制备了一系列由亲水至疏水的具有不同化学组成的单分子层表面. 利用X射线光电子能谱、接触角测试仪和原子力显微镜对其表面性质进行了表征. 对单分子层表面分别进行了多巴及液相环境相关的液滴黏附性能研究, 发现只含有—OH基团的单分子层表面具有最优越的抗多巴黏附能力, 随着表面—OH基团的减少, 多巴的黏附能力增强, —CH₃基团的引入明显增强了多巴在表面的黏附能力; 还发现只含有—OH的单分子层表面具有最大的液滴黏附性能, 随着表面—OH基团的减少, 多巴依附的液相环境中的液滴对表面的黏附能力越来越弱, —CH₃基团的引入明显降低了表面的水滴黏附能力. 实验结果表明, 单一的—OH或—CH₃单分子层表面很难同时具有既抗多巴又抗液滴黏附的性能, 而含有复合官能团的单分子层表面则可以达到这种双重效果. 本文研究可为适应特定环境的抗黏附材料的设计与制备提供依据.

关键词: 多巴, 液滴, 复合官能团单分子层, 黏附力

Abstract:

11-Mercapto-1-undecanol and 1-dodecyl mercaptan with —OH or —CH₃ as capping groups respectively were self-assembled onto gold surfaces at molar ratios of 1:0, 3:1, 1:1, 1:3 and 0:1, prepa-ring binary monolayers with various hydrophilic-hydrophobic properties and chemical compositions. The monolayers were characterized by X-ray photoelectron spectroscopy(XPS), contact angle(CA) and atomic force microscope(AFM) methods. The adhesion properties of dopa and liquid phase environment-related water droplets against self-assembled monolayers(SAMs) were also investigated. It can be found that the OH-terminated SAMs had the most superior anti-dopa adhesion ability. With the molar ratio decrease of —OH groups and the introduction of the —CH₃ groups on the surface, the adhesion ability of dopa to the surface is increased. Furthermore, the pure OH-terminated SAMs showed a strongest droplet adhesion performance, and with the molar ratio of —OH groups decreasing, the droplet adhesion to the surface become weak. The introduction of the —CH₃ groups significantly reduced the surface water adhesion. The experimental results showed that the OH- or CH₃-terminated SAMs is difficult to possess anti-dopa and droplet-adhesion properties at the same time and the adhesion ability of the binary mixed SAMs can be adapted to a specific environment, which proposed a new concept for the design and preparation of anti-adhesion materials.

Key words: Dopa, Droplets, Mixed self-assemded monolayers(SAMs), Adhesion

中图分类号:

TrendMD:

孟秀峰, 翟志伟, 郭爱军. 自组装单分子层对多巴黏附能力的可控性研究. 高等学校化学学报, 2018, 39(10): 2245.

MENG Xiufeng,ZHAI Zhiwei,GUO Aijun. Self-assembled Monolayers for Controllable Adhesion of DOPA^†. Chem. J. Chinese Universities, 2018, 39(10): 2245.

图/表 7

Scheme 1 Scheme of AFM tip preparation

Fig.1 AFM images of different samples under a binary mixture of —OH/—CH3 with molar ratios of 1:0(A), 3:1(B), 1:1(C), 1:3(D) and 0:1(E), respectivelyRMS/nm: (A) 0.582; (B) 0.633; (C) 0.607; (D) 0.667; (E) 0.677.

Fig.2 XPS characterization for different samples under a binary mixture of —OH/—CH3 with molar ratios of 1:0, 3:1, 1:1, 1:3 and 0:1, respectively

Fig.3 Contact angles of different samples under a binary mixture of —OH/—CH3 with molar ratios of 1:0, 3:1, 1:1, 1:3 and 0:1, respectively

Fig.4 Retraction force curves as a function of separation between DOPA-modified AFM tip for different samples under a binary mixture of —OH/—CH3 with molar ratios of 1:0, 3:1, 1:1, 1:3 and 0:1, respectively

Fig.5 Representative histograms of adhesion forces for the different samples(A—E) and comparison of average adhesive forces(F) under a binary mixture of —OH/—CH3 with molar ratios of 1:0(A), 3:1(B), 1:1(C), 1:3(D) and 0:1(E), respectively

Fig.6 Adhesion of water droplets to surface(A) and comparison of average adhesive forces(B) under a binary mixture of —OH:—CH3 with molar ratios of 1:0, 3:1, 1:1, 1:3 and 0:1, respectively

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