Synthesis of Manganese (Ⅱ) Complexes and Simulation for Superoxide Dismutase

Chem. J. Chinese Universities ›› 1993, Vol. 14 ›› Issue (3): 317.

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Synthesis of Manganese (Ⅱ) Complexes and Simulation for Superoxide Dismutase

MEI Guang-Quan, WANG Lu-Yun, LUO Qin-Hui

Coordination Chemistry Institute, Nanjing University, Nanjing, 210008

Received:1992-07-16 Revised:1992-10-24 Online:1993-03-24 Published:1993-03-24

Abstract

Abstract: We synthesized two macrocyclic and one noncyclic manganese ( Ⅱ ) complexes for simulating Mn-superoxide dismutase(SOD).They were characterized by several physical methods and their structures were identified.Among the three complexes the macrocyclic mononuclear complex has a higher SODactivity than that of the manganese ( Ⅱ ) complexes of carboxylates which were considered as being good model compounds of Mn-SOD.The relationship between the SODactivity and structure of the complexes was discussed.

Key words: Manganese complexes, Macrocyclic, Superoxide dismutase, Activity

TrendMD:

MEI Guang-Quan, WANG Lu-Yun, LUO Qin-Hui . Synthesis of Manganese (Ⅱ) Complexes and Simulation for Superoxide Dismutase[J]. Chem. J. Chinese Universities, 1993, 14(3): 317.

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Synthesis of Manganese (Ⅱ) Complexes and Simulation for Superoxide Dismutase

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