Chem. J. Chinese Universities ›› 2022, Vol. 43 ›› Issue (8): 20220150.doi: 10.7503/cjcu20220150

• Physical Chemistry • Previous Articles     Next Articles

Construction of Mn-Cu Bimetal Containing Phyllosilicate Nanozyme and Evaluation of the Enzyme-like Properties

HE Beibei1, YANG Kuihua1, LYU Rui1,2()   

  1. 1.School of Chemistry and Chemical Engineering,Mianyang Teachers’ College,Mianyang 621000,China
    2.School of Environment and Resource,Southwest University of Science and Technology,Mianyang 621010,China
  • Received:2022-03-08 Online:2022-08-10 Published:2022-04-11
  • Contact: LYU Rui E-mail:ruilv01@mtc.edu.cn
  • Supported by:
    the National Natural Science Foundation of China(42061134018)

Abstract:

A Mn-Cu containing bimetallic phyllosilicate(AMCP) was prepared by one-pot sol-gel method, which was verified to present intrinsic laccase-like and peroxidase-like performance. The results indicated that AMCP presented a well confined 2-dimentional layered structure, and the varied valence states arose from Mn and Cu endow it with excellent enzyme-mimetic activities. Moreover, it exhibits superior pH and temperature tolerance comparing with natural analogue, when the temperature was higher than 70 ℃, AMCP retained above 80% activity while natural enzyme was completely deactivated. Besides, it also remained around 90% activity under pH value of 3—9. Finally, the catalytic mechanism indicated the electron transfer between Mn and Cu accelerated the cycle of Cu2+ and Cu+, which could promote the production of ROS and facilitate the catalytic performance of AMCP. This work provides a novel strategy and direction for the customization of high performance, multi-enzyme mimetic nanozyme, which has a potential application prospect on biosensing, disease therapy and environmental remediation.

Key words: Nanozyme, Phyllosilicate, Bimetallic material, Multi-enzyme like activity

CLC Number: 

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