Chem. J. Chinese Universities ›› 1994, Vol. 15 ›› Issue (1): 5.

• Articles • Previous Articles     Next Articles

The Synthesis and Characteristics of Missile Type Porphyrin with Radio Sensitization

LIU Yu-Wen1, XU Jian-Ping1, WANG Xing-Qiao1, CAO Xi-Zhang1, LI Guang2, GAO Ru-Gui2   

  1. 1. Department of Chemistry, Jilin University, Changchun, 130023;
    2. The Tumour Institute of China Medical University
  • Received:1993-03-03 Revised:1993-07-02 Online:1994-01-24 Published:1994-01-24

Abstract: The metronidazole as a radio-sensitizer was chemically combined with protoporphyrin which has shown some orientating effects on cancer cells.The structure of this new compound was confirmed by the UV,IRspectra and elementary analysis.It is found that the porphyrin has shown some potential drug effect in aminal test and the decrease of dosage and reduction of toxicity.

Key words: Anticancer, Radiosensitizer, Protoporphyrin

TrendMD: