Chem. J. Chinese Universities

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Photolithographic Patterning of Hydrogels and Their Applications

LIU Xin1,2, SHEN Zheng1,2, WU Da-Peng1,2, WANG Qi3, QIN Jian-Hua1* , LIN Bing-Cheng1*   

    1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China;
    2. Graduate School of Chinese Academy of Sciences, Beijing 100039, China;
    3. The Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China
  • Received:2007-08-20 Revised:1900-01-01 Online:2008-02-10 Published:2008-02-10
  • Contact: LIN Bing-Cheng, QIN Jian-Hua

Abstract: Hydrogel micropatterns of poly(ethylene glycol) and polyacrylamide were prepared with a facile photolithographic method. Monomer solutions containing photoinitiator were directly polymerized by UV illumination through a transparency photomask, forming 2-dimensional gel patterns on silanized glass surfaces. The chemically patterned surfaces thus prepared could be used as the template for patterning mammalian cells and formation of structured droplets.

Key words: Hydrogel, Photolithographic method, Micropattern, Surface and interface

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