Preparation and Properties of Polyvinye Alconol/Polyvinylpyrrolidone/Iodine Composite Hydrogels

doi:10.7503/cjcu20200245

Abstract

Abstract:

A low-temperature freezing method was used to prepare a PVA/PVP-I composite hydrogel with adjustable mechanical properties by changing the ratio of PVA and iodophor(PVP-I), the freezing time, and the number of freeze-thaw cycles. The mechanical properties, microstructure, iodine release and bacteriostatic property of the composite gel were characterized. The results show that the controllable mechanical properties of the PVA/PVP-I composite hydrogel can meet the demand for wound dressing; the network structure of the composite hydrogel can effectively reduce the decomposition rate of iodine under ultraviolet rays, and achieve sustainable release of iodine, thereby exerting antibacterial properties, broadening the scope of application of iodine disinfectants.

Key words: Polyvinyl alcohol, Iodophor, Hydrogel, Iodine release

CLC Number:

O631

TrendMD:

GONG Yuning, WANG Qi, WANG Honglei, GUAN Shuang. Preparation and Properties of Polyvinye Alconol/Polyvinylpyrrolidone/Iodine Composite Hydrogels[J]. Chem. J. Chinese Universities, 2020, 41(9): 2078.

Figures/Tables 10

References 26

1	Lacey R. W., J. Appl. Bacteriol., 1979, 46(3), 443—449
2	McLure A. R., Gordon J., J. Hosp. Infect., 1992, 21(4), 291—299
3	Ngai I. M., Van Arsdale A., Govindappagari S., Judge N. E., Neto N. K., Bernstein J., Bernstein P. S., Garry D. J., Obstetrics & Gynecology, 2015, 126(6), 1251—1257
4	Lan H., China Animal Health,2004, (9), 39—40(蓝洪. 中国动物保健, 2004, (9), 39—40)
5	Wei D. M.,Xue Y. Q., Liaoning Chemical Industry, 2011, 40(2), 159—162, 166(魏冬梅, 薛永强. 辽宁化工, 2011, 40(2), 159—162, 166)
6	Tong H. S., Chen Y. Y., Chinese Journal of Veterinary Medicine, 2017, 53(9), 115—117(佟海山, 陈遇英. 中国兽医杂志, 2017, 53(9), 115—117)
7	Yan R. X., Water Soluble Polymer, Chemical Industry Press, Beijing, 2010, 249—252(严瑞瑄. 水溶性高分子, 北京: 化学工业出版社, 2010, 249—252)
8	Chen L., Tian Z., Du Y., Biomaterials, 2004, 25(17), 3725—3732
9	Sacco P., Sechi A., Trevisan A., Picotti F., Gianni R., Stucchi L., Fabbian M., Bosco M., Paoletti S., Marsich E., Carbohydr. Polym., 2016, 136, 418—426
10	Mukherjee D., Azamthulla M., Santhosh S., Dath G., Ghosh A., Natholia R., Anbu J., Teja B. V., Muzammil K. M. J., Drug Deliv. Sci. Technol., 2018, 46, 498—510
11	Huang J., Deng Y., Ren J., Chen G., Wang G., Wang F., Wu X., Carbohydr. Polym., 2018, 186, 54—63
12	Li L.Y., Guan S., Yang L., Qin X. Z., Feng W., Chem. Res. Chinese Universities, 2018, 34(2), 311—317
13	Jiang H., Campbell G., Boughner D., Wan W. K., Quantz M., Med. Eng. Phys., 2004, 26(4), 269—277
14	Wang J., Gao C., Zhang Y., Wan Y., Mater Sci. Eng. C: Mater. Biol. Appl., 2010, 30(1), 214—218
15	Lu X. T., Feng W., Wang H. L., Hu Q. Q., Guan S., Guo P. P., Chem. Res. Chinese Universities, 2018, 34(6), 1028—1034
16	Kokabi M., Sirousazar M., Hassan Z. M., Eur. Polym. J., 2007, 43(3), 773—781
17	Peppas N. A., Merrill E. W., J. Appl. Polym. Sci., 1976, 20(6), 1457—1465
18	Yamaura K., Karasawa K., J. Appl. Polym. Sci., 1994, 51(12), 2041—2046
19	Park K. R., Nho Y. C., Radiat. Phys. Chem., 2003, 67(3/4), 361—365
20	Shi Y., Xiong D., Zhang J., Tribol. Int., 2014, 78, 60—67
21	Mansur H. S., Sadahira C. M., Souza A. N., Mansur A. A., Mater. Sci. Eng.: C,2008, 28(4), 539—548
22	Mansur H. S., Costa E. D. S. Jr,, Mansur A. A., Barbosa⁃Stancioli E. F., Mater. Sci. Eng.: C, 2009, 29(5), 1574—1583
23	An Y., Koyama T., Hanabusa K., Shirai H., Ikeda J., Yoneno H., Itoh T., Polymer, 1995, 36(11), 2297—2301
24	Zhao D., Liao G., Gao G., Liu F., Macromolecules, 2006, 39(3), 1160—1164
25	GB/T20944. 1⁃2007, Textiles⁃Evaluation for Antibacterial Activity, Part 1: Agar Diffusion Plate Method,Standards Press of China, Beijing, 2007(中国国家标准化管理委员会. GB/T20944. 1⁃2007. 纺织品抗菌性能的评价, 第1 部分: 琼脂扩散法, 北京: 中国标准出版社, 2007)
26	Peppas N. A., Stauffef S. R., J. Controlled Release, 1991, 16, 305—310

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