Preparation of Poly(p-dioxanone) with High Molecular Weight from Dihydroxyl Terminated Prepolymers Using HDI as Chain Extender

Chem. J. Chinese Universities

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Preparation of Poly(p-dioxanone) with High Molecular Weight from Dihydroxyl Terminated Prepolymers Using HDI as Chain Extender

YANG Ke-Ke, ZENG Qiang, WANG Xiu-Li, ZHU Xiao-Lan, ZHOU Yan, WANG Yu-Zhong*

Center for Degradable and Flame-Retardant Polymeric Materials, College of Chemistry, Sichuan University, Chengdu 610064, China

Received:2007-05-21 Revised:1900-01-01 Online:2007-11-10 Published:2007-11-10
Contact: WANG Yu-Zhong

Abstract

Abstract: Poly(p-dioxanone)(PPDO) is one of most promising biodegradable materials, however its application was restricted because the rigorous synthetic condition and longer reaction time were needed in order to obtain products with a high molecular weight by common ring-opening polymerization. In this work, a new approach was developed by chain extending of dihydroxyl-terminated PPDO prepolymer(HPPDO) using hexamethylenediisocyanate(HDI) as the chain extender in order to obtain high molecular weight PPDO in a short time. HPPDO was prepared by ring-opening polymerization of p-dioxanone(PDO) catalyzed by SnOct₂ and initiated by 1,4-butanediol(BD). The results obtained show that HPPDO prepolymers can react with Hexamethylenediisocyanate effectively, and the molecular weights of the resulting chain-extended products increase several decade times in less than one hour compared with the prepolymers. The highest viscosity-average molecular weight of the resulting polymer can reach 257000 g/mol. Both the prepolymer and the chain extended product were characterized by ¹H NMR.

Key words: Poly(p-dioxanone), 1,4-Butanediol, Hexamethylenediisocyanate, Chain extending

CLC Number:

O633.1

TrendMD:

YANG Ke-Ke, ZENG Qiang, WANG Xiu-Li, ZHU Xiao-Lan, ZHOU Yan, WANG Yu-Zhong*. Preparation of Poly(p-dioxanone) with High Molecular Weight from Dihydroxyl Terminated Prepolymers Using HDI as Chain Extender[J]. Chem. J. Chinese Universities, doi: .

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Preparation of Poly(p-dioxanone) with High Molecular Weight from Dihydroxyl Terminated Prepolymers Using HDI as Chain Extender

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