Preparation of a Novel Thermosensitive and Biodegradable Microgel Particles

Abstract

Abstract: A novel biodegradable and thermosensitive microgel particle was prepared via suspension polymerization of a well-designed biodegradable macromonomer. The macromonomer is composed of amphiphilic block copolymer PEO-PPO-PEO, oligo(ester) and acryloyl end groups. Ammonium persulfate was employed as the initiator and N,N,N',N'-tetramethylethylene-diamine as the accelerator. The resultant hydrogel particles were confirmed to be reversely thermosensitive as well as biodegradable.

Key words: Hydrogel, Thermosensitive, Biodegradability, Microparticle, Macromonomer

CLC Number:

O631

TrendMD:

ZHU Wen, ZHANG Ying, WANG Biao-Bing, DING Jian-Dong. Preparation of a Novel Thermosensitive and Biodegradable Microgel Particles[J]. Chem. J. Chinese Universities, 2005, 26(2): 373.

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Preparation of a Novel Thermosensitive and Biodegradable Microgel Particles

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