Chemical Constituents from Endophytic Phomopsis sp. Lz42 of Maytenus hookeri

Chem. J. Chinese Universities

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Chemical Constituents from Endophytic Phomopsis sp. Lz42 of Maytenus hookeri

YUAN Lin^1,2, MA Juan¹, WANG Ting³, LI Guo-Hong¹, SHEN Yue-Mao¹, ZHAO Pei-Ji^1*

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;
2. Graduate School of the Chinese Academy of Sciences, Beijing 100049, China;
3. School of Pharmacy, Guiyang Medical University, Guiyang 550004, China

Received:2008-04-07 Revised:1900-01-01 Online:2009-01-10 Published:2009-01-10
Contact: ZHAO Pei-Ji

Abstract

Abstract: Endophytes, commonly present in higher plants, are important sources of natural products with pharmaceutical potential. A new sesquiterpenoid, 4-deacetyl-10-oxo-dihydro-botrydial(1), and a new sterol, 22E,24R-5α,8α-epidioxyergosta-6,22-dien-3β-formate(2), were isolated from solid cultures of an endophytic fungal strain Phomopsis species Lz42, cultivated on Maytenus hookeri, together with five related known compounds, 4β-acetoxy-9β-10β-15α-trihydroxyprobotrydial(3), 22E,24R-5α,8α-epidioxyergosta-6,22-dien-3β-ol(4), ergosterol(5), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol(6) and 22E,24R-ergosta-7,22-diene-3β,5α,6β,9α-tetraol(7). Their structures were identified by extensive spectroscopic, experiments especially 2D-NMR.

Key words: Sesquiterpenoid, Sterol, Phomopsis sp. Lz42, Endophyte, Maytenus hookeri

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YUAN Lin^1,2, MA Juan¹, WANG Ting³, LI Guo-Hong¹, SHEN Yue-Mao¹, ZHAO Pei-Ji^1*. Chemical Constituents from Endophytic Phomopsis sp. Lz42 of Maytenus hookeri[J]. Chem. J. Chinese Universities, doi: .

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Chemical Constituents from Endophytic Phomopsis sp. Lz42 of Maytenus hookeri

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