Chem. J. Chinese Universities

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Studies on Ginsenoside Rb1 and Rd Binding to Cytochrome c by Electrospray Ionization Mass Spectrometry

ZHANG Hua-Rong, ZHANG Han-Qi, WANG Yu-Tang, LI Dan, DING Lan   

  1. College of Chemistry, Jilin University, Changchun 130012, China
  • Received:2006-01-12 Revised:1900-01-01 Online:2006-11-10 Published:2006-11-10
  • Contact: DING Lan

Abstract: Electrospray ionization mass spectrometry was applied to investigating the noncovalent interaction between ginsenosides and cytochrome c. Several noncovalent complexes with different stoichiometric relationships were observed from the mass spectra. The competition experiment was performed to validate the results. The dissociation constants of the complexes obtained by different systems are consistent with each other.

Key words: Electrospray ionization mass spectrometry, Ginsenoside, Cytochrome c, Noncovalent complex

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