Preparation and Performance of p-tert-Butyl-calix[8]-arene-bonded Silica Gel for Capillary Electrochromatography

Abstract

Abstract: A new method for the preparation of calix-arene-bonded stationary phases(C8BS) was developed via the breaking epoxy group on the solid surface of the bonded 3-glycidoxypropyl silica by using active phenolic sodium of calix-arene in the presence of phase-transfer catalyst, which is moderate and universal. The new method was first introduced to the preparation of calixarene-bond stationary phase for capillary electrochromatography(CEC) with some modification. The new stationary phases were evaluated by the pressurized CEC(pCEC). The results show that the calixarene-bonding can provide lower and stable EOF over a wide pH range from 3-8, and the peak shapes of basic compounds on silica gel matrix can be improved because of the shield effect of the macrocyclic ligand, which are very important to CEC. Additionally, EOF source was studied by using silanization step by step. The result shows that the phenolic hydroxyl groups on the calixarene-bonded stationary phase result in EOF partially, which is consistent with the open-column of CEC reported.

Key words: Calixarene-bonded silica gel stationary phase, Pressurized capillary electrochromatography, Electrochromatographic evaluation, Electrosmotic flow

CLC Number:

O657

TrendMD:

LI Lai-Sheng, DA Shi-Lu, FENG Yu-Qi, LIU Min. Preparation and Performance of p-tert-Butyl-calix[8]-arene-bonded Silica Gel for Capillary Electrochromatography[J]. Chem. J. Chinese Universities, 2005, 26(7): 1228.

References

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