Construction of Anti-bacterial Multilayer Films via Layer-by-layer Electro Static Self-assembly of Chitosan and Heparin

Abstract

Abstract: Chitosan as an antibacterial agent and heparin as an anti-adhesive agent were alternatively deposited onto aminolyzed poly(ethylene terephthalate)(PET) to construct anti-adhesive and antibacterial multilayer films.The contact angle and UV data verified the progressive build-up of the multilayer film by alternate deposition of the polyelectrolytes.PRT experiment and in vitro antibacterial assay indicated that the multilayer-modified PET films had much better hemocompatibility and much stronger antibacterial performance than(unmodified) PET.Such an easy processing and shape-independent method to prepare an anti-adhesive and(antibacterial) surface may have a good potential for surface modification of cardiovascular devices.

Key words: Antibacterial multilayer films, Layer-by-layer self-assembly, Polyester, Surface modification

CLC Number:

O631

TrendMD:

YUAN Wei-Yong, JI Jian, FU Jin-Hong, SHEN Jia-Cong . Construction of Anti-bacterial Multilayer Films via Layer-by-layer Electro Static Self-assembly of Chitosan and Heparin[J]. Chem. J. Chinese Universities, 2005, 26(10): 1963.

[1]	ZHAO Sheng, HUO Zhipeng, ZHONG Guoqiang, ZHANG Hong, HU Liqun. Preparation of Modified Gadolinium/Boron/Polyethylene Nanocomposite and Its Radiation Shielding Performance for Neutron and Gamma-ray [J]. Chem. J. Chinese Universities, 2022, 43(6): 20220039.
[2]	MA Yukun, JIN Hui, REN Chuanli, LI Zhibo. Ring-opening Polymerization of Cyclic Esters Using Recyclable Polystyrene Supported Urea-Base Binary Catalyst [J]. Chem. J. Chinese Universities, 2021, 42(9): 2968.
[3]	SHI Ying, HU Guangjian, WU Minjie, LI Feng. Applications of Low Temperature Plasma for the Materials in Li-ion Batteries [J]. Chem. J. Chinese Universities, 2021, 42(5): 1315.
[4]	JI Shaobo, CHEN Xiaodong. Surface and Interface Chemistry in Flexible Electronics [J]. Chem. J. Chinese Universities, 2021, 42(4): 1074.
[5]	LI Chen, LI Yuesheng. Living Ring-opening Polymerization of O-Carboxyanhydrides Catalyzed by Pyridine Derivatives [J]. Chem. J. Chinese Universities, 2021, 42(10): 3203.
[6]	YAN Fanyong, SUN Zhonghui, PANG Jiping, JIANG Yingxia, CHEN Yuan. Functionalized Carbon Dots of Benzothiazine Derivatives for Detection of Quercetin in Ginkgo Biloba Tea [J]. Chem. J. Chinese Universities, 2020, 41(8): 1768.
[7]	XIA Yun, Lü Wangyang, CHEN Wenxing, LI Nan. Fiber Supported Carbon Black Metal Phthalocyanine Axial Complex to Mimic Enzyme for Highly Efficient Catalytic Degradation of Organic Pollutant in Water^† [J]. Chem. J. Chinese Universities, 2020, 41(7): 1582.
[8]	PENG Xinyan, LIU Yunhong, LI Jiawen, FENG Yilong, WANG Hanchun. Preparation and Characterization of Tannin/Zwitterionic Modified Oil-water Separation Membrane ^† [J]. Chem. J. Chinese Universities, 2020, 41(6): 1337.
[9]	CHEN Liangdan,ZOU Wei,WU Liang,XIA Fanjie,HU Zhiyi,LI Yu,SU Baolian. Nano-Al₂O₃ Coated Li-rich Cathode Material Li_{1. 2}Ni_0.13Co_0.13Mn_0.54O₂ for Highly Improved Lithium-ion Batteries ^† [J]. Chem. J. Chinese Universities, 2020, 41(6): 1329.
[10]	LIU Shuaizhuo,ZHANG Qian,LIU Ning,XIAO Wenyan,FAN Leiyi,ZHOU Ying. One-step Synergistic Hydrophobic Modification of Melamine Sponge and Its Application ^† [J]. Chem. J. Chinese Universities, 2020, 41(3): 521.
[11]	ZHANG Xinyu, WANG Hong, FANG Yun, FAN Ye. Stimuli-responsive Fe₃O₄ Nanoparticle Modified by Conjugated Linoleic Acid [J]. Chem. J. Chinese Universities, 2020, 41(11): 2519.
[12]	WANG Zhenyu, LI Jianhua, GUO Huijun, YANG Chuncai. In situ Synthesis of Nano-sized Silica Enforced Anionic Polyester Sizing Agent and Its Effect on ILSS of Carbon Fiber Composites ^† [J]. Chem. J. Chinese Universities, 2019, 40(9): 2005.
[13]	MAO Long, LIU Yuejun, FAN Shuhong. Preparation and Properties of Polypyrrole Modified Layered Clay/poly(ε-caprolactone) Antibacterial Nanocomposites [J]. Chem. J. Chinese Universities, 2019, 40(8): 1726.
[14]	SUI Jiayang, LIU Xiaoyang, QIAN Miaomiao, ZHU Yanchao, XUE Beichen, FENG Yi, TIAN Yumei, WANG Xiaofeng. Surface Modification of Silica/carbon Black Derived from Rice Husks and Its Influence on Natural Rubber Composites^† [J]. Chem. J. Chinese Universities, 2019, 40(7): 1561.
[15]	LI Juan, DU Fanfan, FENG Rui, HU Qian, JIE Suyun, LI Bogeng. Synthesis of Cyclic and Linear Block Copolyesters via Ring-opening Copolymerization of ε-Caprolatone and L-Lactide Catalyzed by Zinc Complex^† [J]. Chem. J. Chinese Universities, 2018, 39(6): 1297.

Construction of Anti-bacterial Multilayer Films via Layer-by-layer Electro Static Self-assembly of Chitosan and Heparin

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments