Studies on the Aconitum Alkaloids in the Sini Concoction by Electrospray Ionization Mass Spectrometry

Abstract

Abstract: Electrospray ionization mass spectrometry(ESI-MS) was used for the analysis of the aconitum alkaloids in the complex prescription of TCM, Sini concoction, which consists of prepared aconite roots, liquorice and dried ginger, without needing chromatographic separation. [M⁺H]+ are formed for aconitum alkaloids in the positive ion mode. Eighteen aconitum alkaloids including benzoylaconines, aconitines and lipo-alkaloids were found. Benzoylaconines were detected as the main aconitum alkaloids in Sini concoction.

Key words: Electrospray ionization mass spectrometry, Sini concoction, Aconitine, Mono-ester aconitum alkaloids

CLC Number:

O657

TrendMD:

WANG Yong, SONG Feng-Rui, JIN Dong-Ming, LIU Zhi-Qiang, LIU Shu-Ying . Studies on the Aconitum Alkaloids in the Sini Concoction by Electrospray Ionization Mass Spectrometry[J]. Chem. J. Chinese Universities, 2004, 25(1): 85.

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