Chem. J. Chinese Universities ›› 2003, Vol. 24 ›› Issue (2): 249.

• Articles • Previous Articles     Next Articles

Studies on the Interactions Between Morin and Its Cu(Ⅱ)-, Zn(Ⅱ)-Complexes with DNA

SONG Yu-Min, KANG Jing-Wan, LU Xiao-Quan, WANG Zhi-Hua, GAO Jin-Zhang   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China
  • Received:2001-09-11 Online:2003-02-24 Published:2003-02-24

Abstract: The interactions of Morin and its Cu(Ⅱ)-, Zn(Ⅱ)-complexes with calf thymus DNA have been studied by using fluorimetric and electrochemical methods. Cu(Ⅱ)-, Zn(Ⅱ)-complexes have different spectra and electrochemical characteristics from that of Morin in the presence of DNA. The results suggest that Morin and its complexes can both bind to DNA, but the binding mode is different. The complexes bind to DNA mainly like EB by intercalation, while Morin binds in a non-intercalating mode.

Key words: Morin, Complex, DNA, Binding mode, Fluorescence

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