Preparation and Characterization of Cell Compatible Polyurethane

Abstract

Abstract: Cell compatible polyurethane(PU) was obtained by surface photo-grafting of 2-hydroxyethyl acrylate(HEA) onto PUmembrane surface. Hydroperoxide groups were introduced onto PUmembrane surface by photo-oxidization, then the oxidized membrane, immersed previously in monomer solution, was irradiated under UVlight. The grafted copolymers were characterized by ATR-FTIRspectra, element spectroscopy for chemical analysis(ESCA) and static water contact angle. The results showed that grafting was confined within the surface layer. Cell compatible study revealed that the attachment and growth of human umbilical vein endothelial(HUVE) cells were improved after HEAgrafting. Cells grew faster on the surface with higher oxygen content.

Key words: Polyurethane, Grafting polymerization, 2-Hydroxyethyl acrylate, Human umbilical vein endothelial cell, Cell compatibility

CLC Number:

O632

TrendMD:

GUAN Jian-Jun, GAO Chang-You, SHEN Jia-Cong . Preparation and Characterization of Cell Compatible Polyurethane[J]. Chem. J. Chinese Universities, 2001, 22(2): 317.

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Preparation and Characterization of Cell Compatible Polyurethane

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