Grafting Modification and Thermosensitive Properties of Polyurethane Microspheres†

doi:10.7503/cjcu20131139

Abstract

Abstract:

Surface modification of polyurethane microspheres(PUS) by grafting poly(N-isopropylacrylamide)(PNIPAAm) was initiated under UV light. Besides benzophenone(BP) was used as a photosensitizer, ammoniumperoxydisulfate(APS) was used as a free radical initiator. The occurrence of grafting copolymerization of PNIPAAm was testified by the attenuated total multiple reflection technique(ATR-IR). Scanning electron micrograph(SEM) showed that the surface morphology of PUS changed significantlyafter modification. The lower critical solution temperature(LCST) of the PUS was determined by differential scanning calorimetry(DSC), and the wettability of the membrane assembled by PU microspheres was investigated by water contact angle measurement. The results showed that the grafting yield increased with irradiation time and finally reached the saturation value. As the concentration of APS initiator was increased, the grafting yield had a maximum. In addition, the modified PU microspheres were thermosensitive similar to that of PNIPAAm gel, and the LCST was determined about 35 ℃. The water contact angle measurement proved that the PNIPAAm-g-PU microspheres demonstrated good hydrophilic behavior below the LCST.

Key words: Polyurethane microsphere, Poly(N-isopropylacrylamide), Thermosensive, Grafting polymerization

CLC Number:

O631

TrendMD:

GONG Mei, ZHANG Li, HUANG Di, DU Jingjing, ZHOU Minbing, LI Yubao, XIE Huiqi. Grafting Modification and Thermosensitive Properties of Polyurethane Microspheres^†[J]. Chem. J. Chinese Universities, 2014, 35(8): 1843.

Figures/Tables 7

Fig.1 Schematic representation of photografting process of PNIPAAm on the surface of PU microspheres

Fig.2 Effect of irradiation time(A) and APS initiator concentration(B) on the grafting yield of PNIPAAm

Fig.3 ATR-FTIR spectra for PU microspheres(a) and PU-g-PNIPAAm microspheres(b) APS concentration is 3% and the grafting time is 40 min.

Fig.4 SEM images of PU(A) and PU-g-PNIPAAm microspheres(B)(3%APS, grafting time: 40 min) Inset: particle-size distribution graph of microspheres.

Fig.5 DSC curves of PU microspheres(a) and PUS-g-PNIPAAm microspheres(b)

Fig.6 SEM image of PU microspheres membrane(A), water contact angle(CA) of PUS(B) and PUS-g-PNIPAAm(C) membranes at 25 ℃

Fig.7 Swelling ratio of PUS-g-PNIPAAm membranes

References 18

[1]	Wang D. P., Yang M. Q., Dong Z. X., Bo S. Q., Ji X. L., Chem. J. Chinese Universities, 2012, 33(11), 2567—2572
	(王大鹏, 杨木泉, 董志鑫, 薄淑芹, 姬相玲. 高等学校化学学报, 2012, 33(11), 2567—2572)
[2]	Ren S. D., Chen D. Y., Jiang M., Chem. J. Chinese Universities, 2010, 31(1), 167—171
	(任申冬, 陈道勇, 江明. 高等学校化学学报, 2010, 31(1), 167—171)
[3]	Shantha K. L., Harding D. R. K., Int. J. Pharm., 2000, 207(1/2), 65—70
[4]	ChengS. X., Zhang J. T., Zhuo R. X., J. Biomed Mater. Res., 2003, 67A(1), 96—103
[5]	Liang L., Shi M. K., Viswanathan V. V., Peurrung L. M., Young J. S., J. Membr. Sci., 2000, 177(1/2), 97—108
[6]	Hearon K., Besset C. J., Lonnecker A. T., Ware T., Viot W. E., Wilson T. S., Wooley K. L., Maitland D. J., Macromolecules, 2013, 46(22), 8905—8916
[7]	Lu J., Li J., Yi M., Ha H. F., Radiat. Phys. Chem., 2001, 60(6), 625—628
[8]	Roy D., Semsarilar M., Guthrie J. T., Perrier S., Chem. Soc. Rev., 2009, 38(7), 2046—2064
[9]	Buck D. W. Ⅱ, Alam M., Kim J. Y., J. Plast. Reconstr. Aes., 2009, 62(1), 11—18
[10]	Kim K. J., Lee H. W., Lee M. W., Choi J. H., Moon K. C., Koh J. K., Dermatol. Surg., 2004, 30(4), 545—547
[11]	Freiberg S., Zhu X. X., Int. J. Pharm., 2004, 282(1/2), 1—18
[12]	Fundueanu G., Constantin M., Stanciu C., Theodoridis G., Ascentzi P., J. Mater. Sci. Mater Med, 2009, 20(12), 2465—2475
[13]	Kim E. J., Cho S. H., Yuk S. H., Biomaterials, 2001, 22(18), 2495—2499
[14]	Sanborn T. J., Messersmith P. B., Barron A. E., Biomaterials, 2002, 23(13), 2703—2710
[15]	Ino K., Ito A., Honda H., BiotechnolBioeng, 2007, 97(5), 1309—1317
[16]	Ito A., Akiyama H., Kawabe Y., Kamihira M., J. Biosci. Bioeng., 2007, 104(4), 288—293
[17]	Collier J. H., Hu B. H., Ruberti J. W., Zhang J., Shum P., Thompson D. H., Messersmith P. B., J. Am Chem. Soc., 2001, 123(38), 9463—9464
[18]	Luo N., Wang D. N., Ying S. K., Macromolecules, 1997, 30(15), 4405—4409
	(Ed.: W, Z)