Chem. J. Chinese Universities ›› 1998, Vol. 19 ›› Issue (6): 899.

• Articles • Previous Articles     Next Articles

Studies on Bio rational Design of Photosystem Ⅱ Inhibitors(Ⅱ) ——The Crystal and Molecular Structure of Ethyl 3-Benzylamino-2-cyano-3-methylthioacrylate

LIU Hua-Yin1, YANG Guang-Fu1, LU Rong-Jian1, TAN Hui-Fen1, YANG Hua-Zheng1, LAI Lu-Hua2   

  1. 1. The Institute of Elemento-Organic Chemistry, National Elemento-Organic Chemistry Key Laboratory, Nankai University, Tianjin, 300071;
    2. The Institute of Physical Chemistry, Perking University, Beijing, 100871
  • Received:1997-06-03 Online:1998-06-24 Published:1998-06-24

Abstract: Based on the structure of D1 protein of photosystem Ⅱ of Pisum sativum, the title compound with good Hill reaction inhibition was designed and synthesized, and its structure was confirmed by X-ray diffraction. It was found that the CH2 group between phenyl and amino is important for compound's inhibition, and there is no H-binding in the molecule.

Key words: Acrylates, Photosystem Ⅱ inhibitors, X-ray diffraction, Crystal structure

CLC Number: 

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