Preparation and Chromatographic Characteristics of Fused Silica Capillary Column Based on Tetra-o-benzylated Calix[4]arene

Abstract

Abstract: 5-1',1'-Dimethylundecenyloxyphenylmethyl-11,17,23 tri 1",1" -dimethylethyl-25,26,27,28-tetrahydroxycalixarene was synthesized from 1,1-dimethylundecenyloxyphenylmethylphenol and bishydroxymethylated p tert butylphenol formaldehyde trimer (3-[3-[3-(hydroxymethyl)-5-tert butylsalicyl]-5-tert-butylsalicyl]-5-tert-butyl-2-hydroxybenzyl-alcohol) by '3+'1 fragment condensation in dioxane with TiCl₄ as condensation agent. It was subjected to benzylation with benzyl chloride in NaOHaqueous solution in the presence of Bu₄N⁺Br^- as PTCagent. The yield of the tetra-o-benzylated calix[4]arene was 78%. The tetra-o-benzylated calix[4]arene and OV-1701 were crosslinked in situ with DCUPonto the surface of fused silica capillary column. The resulted column exhibited high column efficiency(4379 plates/m, naphthalene 120 ℃) and excellent separation abilities for various positional isomers.

Key words: Calix[4]arene, Capillary chromatography, Stationary phase

CLC Number:

O657.71

TrendMD:

CHEN Yuan-Yin, TANG Xing-Hua, LU Xue-Ran, ZENG Zhao-Rui, WANG Jian-Ling . Preparation and Chromatographic Characteristics of Fused Silica Capillary Column Based on Tetra-o-benzylated Calix[4]arene[J]. Chem. J. Chinese Universities, 1998, 19(5): 717.

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Preparation and Chromatographic Characteristics of Fused Silica Capillary Column Based on Tetra-o-benzylated Calix[4]arene

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